Clodronate Liposomes & Fluorescent Dil Liposomes
氯膦酸盐脂质体和荧光素Dil脂质体（Clodronate Liposomes & Fluorescent Dil Liposomes）用于在实验动物体内或体外清除和示踪单核巨噬细胞，为即用型试剂，可直接使用。标记有荧光素DiI的对照脂质体可用于研究通过特定给药途径注射的脂质体是否能够到达待研究的巨噬细胞。还可以显示通过这种途径注射的脂质体到达的其他巨噬细胞种群。
Artificial spheres consisting of concentric phospholipid bilayers encapsulating an aqueous PBS (phosphate buffered saline) solution containing clodronate. Liposomes are particles, sized at a max. of 3 micron. They form a suspension in PBS and will tend to precipitate upon storage, forming a pellet on the bottom of the tube or flask. The suspension should be shaken before administration to laboratory animals in order to recover the homogeneous suspension. The concentration of clodronate in the suspension is ca. 5 mg/ml.
Control liposomes, labeled with the fluorochrome DiI can be used to investigate whether liposomes injected via a particular administration route are able to reach the macrophages to be studied. They can also show other macrophage populations reached by the liposomes injected via this route.