Murine Anti-Factor X抗体(GMA-529)
货号：GMA-529
|
规格：0.1 mg
|
价格：￥0.00
|
品牌：Greenmoab
Factor X抗体,Murine Anti-Factor X抗体(GMA-529)推荐用于ELISA,Immunoblotting和Inhibition应用。
Factor X抗体
产品名称:
Murine Anti-Factor X抗体
Clone GMA-529
描述:
Factor X (Mr 59,000) is a vitamin K-dependent plasma protein zymogen that plays a central role as the substrate for both the intrinsic (factor VIIa, tissue factor) and extrinsic (factor IXa, factor VIIIa) pathways. In the presence of cofactor factor Va, phospholipid, and Ca2+, activated factor X cleaves two peptide bonds in prothrombin to form thrombin. GMA-529 (also known as α-HFX-27) binds human factor X and Xa in solid-phase ELISA and Western blot. GMA-529 prolonged FX-dependent clotting time, and activated partial thromboplastin time of normal plasma, and showed inhibition of thrombin generation.1
物种反应性:
Human
来源:
Murine
特异性:
Factor X/Xa
免疫原:
Human Factor X
同型:
IgG1
应用
ELISA:
Binds immobilized human factor X and factor Xa. Does not bind mouse FX.
Immunoblotting:
Binds human factor X and Xa under non-reduced conditions. Does not blot reduced FX/Xa.
Inhibition:
Inhibits thrombin generation, prolongs clotting time.
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