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Murine Anti-Factor VIII抗体(GMA-8012)
货号：GMA-8012 | 规格：0.5 mg | 价格：￥0.00 | 品牌：Greenmoab
Factor VIII抗体,Murine Anti-Factor VIII抗体(GMA-8012)推荐用于ELISA和Inhibition应用。
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Factor VIII抗体

产品名称:

Murine Anti-Factor VIII抗体


Clone GMA-8012

描述:
Factor VIII (FVIII) is a heterodimer consisting of a heavy chain (ranging in mass from 90 to 200 kDa) bound via metal ions to a light chain (80 kDa). In plasma, FVIII circulates in an inactive form bound to von Willebrand factor. Following activation by factor Xa or thrombin, factor VIIIa can function as cofactor for the enzyme factor IXa in the activation of factor X in the presence of phospholipid and Ca2+. Absent or defective FVIII is the cause of the X-linked recessive bleeding disorder hemophilia A. GMA-8012 (also known as 3B10 or 3B10.5B) recognizes the A1-A3 domain of FVIII, is slightly inhibitory, and is suitable for ELISA and bio-layer interferometry pairing experiments.


物种反应性: Human, Mouse, Pig

来源: Murine

特异性: A1A3 domain

免疫原: B-domain deleted recombinant Human Factor VIII

同型: IgG2a

应用
ELISA: Binds the A1A3 domain of recombinant human factor VIII in solid-phase ELISA.

Inhibition: Slightly inhibitory in aPTT clotting assay.
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