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Anti-ATXN3 Antibody
货号:AB0089-500 | 规格:1.5 mg | 价格:¥0.00 | 品牌:SICGEN
SICGEN ATXN3抗体/Anti-ATXN3 Antibody经验证适用于WB,众多文献引用,质保期一年。
ATXN3抗体

描述:Goat polyclonal antibody to ATXN3. This protein appears to be a component of the ubiquitin proteasome system and has deubiquitinase activity. It may also have roles in neuroprotection, protein homeostasis maintenance, transcriptional and cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. The protein contains Qn repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease also known as spinocerebellar ataxia-3, an autosomal dominant neurologic disorder.

别名:AT3, ATX3, ataxin-3, ataxin 3 variant h, autosomal dominant ataxin 3, ataxin 3 variant m, ataxin 3 variant ref, JOS, josephin, Machado-Joseph, Machado-Joseph disease protein 1, MJD, MJD1, SCA3, spinocerebellar ataxia 3, olivopontocerebellar ataxia 3, spinocerebellar ataxia type 3 protein antibody.

浓度: 3 mg/ml

抗体类型: 一抗.

Target Name: Anti-ATXN3

Accession Number: ENSG00000066427

宿主: Goat

免疫原物种: Human

免疫原类型: Recombinant protein

免疫原: Purified recombinant peptide derived from within residues 120 aa to 250 aa of human ATXN3 produced in E. coli.

亚型: IgG

克隆: Polyclonal

已确认的反应种属: Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other

特异性: Detects levels of ATXN3 protein in transfected cells with GFP-ATXN3 and endogenous levels in U118, SH-SY5Y, At-T20 and hTERT cell lysates by Western blot. This Ab is similar to AB10089.

储存缓冲液: PBS, 20% glycerol and 0.05% sodium azide

纯化: Epitope affinity purified

偶联物: Unconjugated

RRID: AB_2333113

经验证的应用: WB

推荐稀释: WB:1:250-1:2,000

储存条件: Store at -20 C for long-term storage. Store at 2-8 C for up to one month.



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