LC-SPDP Crosslinker
货号：c1117-1gm
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规格：1 gram
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价格：￥0.00
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品牌：ProteoChem
LC-SPDP Crosslinker 是由北京中昊新生科技有限公司提供.ProteoChem致力于蛋白生物化学和有机合成领域的生物试剂和化学试剂研发，生产NMR、质谱、蛋白偶联剂以及新型蛋白质组学试剂的分析标准品，用于质谱，药物研发，诊断和蛋白生物中的蛋白检测和蛋白修饰等方面。
LC-SPDP crosslinker, Succinimidyl 6-(3-[2-pyridyldithio]-propionamido)hexanoate, is a cleavable, water insoluble, amino and thiol (sulfhydryl) reactive heterobifunctional protein crosslinker. The "long chain" LC-SPDP crosslinking reagent has a 15.7 angstrom spacer arm, compared to the shorter 6.8 angstrom spacer arm version of SPDP crosslinker. Often, due to steric hindrances, it is desirable to empirically test which of the two LC-SPDP crosslinker versions will work best in your specific crosslinking application.
LC-SPDP crosslinker's reactive moites consist of an N-hydroxysuccinimide (NHS) ester that reacts with primary amines, as found in lysine side chains. While on the other end of the LC-SPDP crosslinker molecule pyridinyldisulfide reacts with sulhydryls to yield a reducible disulfide bond which can be reduced with TCEP-HCl or DTT to reverse the crosslinked proteins.
Molecular Weight: 425.5
Spacer Length: 15.7 Å
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