NuGel™ Poly-Amine For Immobilization

Non-specific sites are virtually eliminated by a polymer coating
Stable across a wide pH range 2 – 10
1000Å, 50µm Silica suitable for LC and batch processes
Applications include: Enzyme immobilization, separation and purification of biopolymers, immobilization of proteins & ligands – monoclonal antibodies, hormones, peptides, haptens, drugs, etc.
Silica has been an industry standard as an advantageous matrix suitable for high performance liquid chromatography. With NuGel™, non-specific sites have been virtually eliminated making it an ideal support for affinity purification. Through a proprietary polymer coating, Silica is crosslinked forming a reactive Poly-Epoxy functionality stable across a wide pH range (pH 2 to 10). From this foundational chemistry, all of the NuGel™ affinity products are derived.

NuGel™ Poly-Amino Technical Data

NuGel™ Poly-Amino is a derivative of NuGel™ polyhydroxy affinity support. This affinity support contains amino groups at the end of hydrophilic spacer arms and is used to couple ligands containing carboxyl, aldehyde, anhydride and epoxy groups.

Special Features:

Couples ligands containing free carboxyl groups in the presence of a carbodiimide.
Couples ligands containing free aldehyde, anhydride and epoxy groups.
Couples non-polar ligands in organic solvents.
pH stable from 2 to 9.