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抗人CD11a(38)抗体

货号:ICH1006-100mg 品牌:ichorbio

产品特性

Bulk Anti-Human CD11a (38) Antibody is manufactured in an cGMP compliant facility.
内毒素: ≤ 1.0 EU/mg as determined by the LAL method
纯度: >95% by SDS-PAGE and HPLC
应用: Flow Cytometry, Western Blot, IHC (Frozen), Immunofluorescence, Immunoprecipitation.
规格 价格
100mg 咨询
产品咨询:info@biopcr.com
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详细介绍

产品名称:抗人CD11a(38)抗体
别名:抗人CD11a抗体, Bulk Anti-Human CD11a (38) Antibody, Anti-Human CD11a Antibody, LFA-1 alpha, LFA-1A, Integrin alpha-L, ITGAL
宿主:Mouse
应用:Flow Cytometry, Western Blot, IHC (Frozen), Immunofluorescence, Immunoprecipitation
亚型:Mouse IgG2a
克隆:38
浓度:1.0 - 5.0 mg/ml
免疫原:Unknown
反应性:Human
特异性:Anti-CD11a In Vivo Antibody - Low Endotoxin (38) recognizes Human CD11a. Anti-Human CD11a (Anti-LFA-1a) recognizes the (Mr 175 kDa) a chain of the leukocyte function associated antigen-1 (LFA-1). The leukocyte integrin LFA-1 is a member of a family of heterodimeric receptors that mediate divalent cation-dependent cellular adhesion reactions. LFA-1A binds to domain 1 of an intercellular adhesion molecule (ICAM) on target tissues.
存储溶液:0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
储存条件:anti-CD11a In Vivo Antibody - Low Endotoxin (38) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
推荐同型对照(Isotype Control):Mouse IgG2a In Vivo Isotype Control - Low Endotoxin [C1.18.4] (ICH2245)
推荐缓冲液(Buffer):体内抗体缓冲液pH5.0; 体内抗体缓冲液pH7.4; 体内抗体缓冲液pH8.0
靶点(Target): CD11a
UniProt: :P20701
纯化方法(Purification method): This monoclonal antibody was purified using Protein A
抗原分布(Antigen Distribution):The CD11a antigen is present on most leukocytes and plays a vital role in cellular immune responses which require adhesion. Lymphocyte activation via the T-cell antigen receptor (TCR) up-regulates LFA-1 function. The absence of LFA-1A or B may induce the disease state known as leukocyte adhesion deficiency (LAD). Tumor cells which do not express LFA-1 may have avoided cellular immune-responses such as those carried out by natural killer cells (NK).
背景资料(Background): :Anti-CD11a may be used to study a variety of biological phenomena related to the function of cell adhesion molecules. This antibody may be used to study transplantation rejections and to assist in characterizing lymphomas and leukemias.
纯度(Purity): :>95% by SDS-PAGE and HPLC
内毒素(Endotoxin): :≤ 1.0 EU/mg as determined by the LAL method
聚集(Aggregation): :Aggregation level ≤ 5%
应用说明(Application Notes): :Each investigator should determine their own optimal working dilution for specific applications.
产品使用(Use): :Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件: :Blue ice
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