抗人CD28(CD28.2)抗体
货号：ICH1013-25mg
品牌：ichorbio
产品特性
Bulk Anti-Human CD28 (CD28.2) Antibody is manufactured in an cGMP compliant facility.
内毒素: <0.1 EU/mg as determined by the LAL method
纯度: >95% by SDS-PAGE and HPLC
应用: IHC (Frozen), Flow Cytometry, Functional Assays.
| 规格 | 价格 |
|---|---|
| 25mg | ￥咨询 |
产品咨询：info@biopcr.com
产品订购：sales@biopcr.com
技术支持：tech@biopcr.com
服务热线：400-860-6200
详细介绍
产品名称：抗人CD28(CD28.2)抗体
别名：抗人CD28抗体, Bulk Anti-Human CD28 (CD28.2) Antibody, Anti-Human CD28 Antibody, TP44
宿主：Mouse
应用：IHC (Frozen), Flow Cytometry, Functional Assays
亚型：Mouse IgG1 Kappa
克隆：CD28.2
浓度：1.0 mg/ml
反应性：Human
特异性：Anti-CD28 In Vivo Antibody - Low Endotoxin (CD28.2) recognizes an epitope on Human CD28
存储溶液：0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
储存条件：anti-CD28 In Vivo Antibody - Low Endotoxin (CD28.2) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
推荐同型对照（Isotype Control）：Mouse IgG1 Isotype Control for In Vivo - Low Endotoxin [HKSP] (ICH2247)
推荐缓冲液（Buffer）：体内抗体缓冲液pH5.0； 体内抗体缓冲液pH7.4； 体内抗体缓冲液pH8.0
靶点（Target）: CD28
UniProt: ：P10747
纯化方法（Purification method）: This monoclonal antibody was purified using Protein A
抗原分布（Antigen Distribution）：Mature T cells, thymocytes, NK cell subsets, plasma cells, EBV-positive B cells
背景资料（Background）: ：CD28 (Cluster of Differentiation 28) is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is composed of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. It is expressed on the cell surface as disulfide-linked homodimer or as monomer. CD28 is the receptor for B7.1 (CD80) and B7.2 (CD86). When activated by Toll-like receptor ligands, the B7.1 expression is upregulated in antigen presenting cells (APCs). The B7.2 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. Stimulation through CD28 in addition to the TCR can provide a potent co-stimulatory signal to T cells for the production of various interleukins (IL-2 and IL-6 in particular). CD28 possesses an intracellular domain with several residues that are critical for its effective signalling. CD28 also contains two proline-rich motifs that are able to bind SH3-containing proteins. CD28 has also been found to stimulate eosinophil granulocytes where its ligation with anti-CD28 leads to the release of IL-2, IL4, IL-13 and IFN-gamma
纯度（Purity）: ：>95% by SDS-PAGE and HPLC
内毒素（Endotoxin）: ：<0.1 EU/mg as determined by the LAL method
聚集（Aggregation）: ：Aggregation level ≤ 5%
应用说明（Application Notes）: ：Each investigator should determine their own optimal working dilution for specific applications.
产品使用（Use）: ：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件: ：Blue ice
返回列表
推荐缓冲液（Buffer）：体内抗体缓冲液pH5.0； 体内抗体缓冲液pH7.4； 体内抗体缓冲液pH8.0
靶点（Target）: CD28
UniProt: ：P10747
纯化方法（Purification method）: This monoclonal antibody was purified using Protein A
抗原分布（Antigen Distribution）：Mature T cells, thymocytes, NK cell subsets, plasma cells, EBV-positive B cells
背景资料（Background）: ：CD28 (Cluster of Differentiation 28) is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is composed of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. It is expressed on the cell surface as disulfide-linked homodimer or as monomer. CD28 is the receptor for B7.1 (CD80) and B7.2 (CD86). When activated by Toll-like receptor ligands, the B7.1 expression is upregulated in antigen presenting cells (APCs). The B7.2 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. Stimulation through CD28 in addition to the TCR can provide a potent co-stimulatory signal to T cells for the production of various interleukins (IL-2 and IL-6 in particular). CD28 possesses an intracellular domain with several residues that are critical for its effective signalling. CD28 also contains two proline-rich motifs that are able to bind SH3-containing proteins. CD28 has also been found to stimulate eosinophil granulocytes where its ligation with anti-CD28 leads to the release of IL-2, IL4, IL-13 and IFN-gamma
纯度（Purity）: ：>95% by SDS-PAGE and HPLC
内毒素（Endotoxin）: ：<0.1 EU/mg as determined by the LAL method
聚集（Aggregation）: ：Aggregation level ≤ 5%
应用说明（Application Notes）: ：Each investigator should determine their own optimal working dilution for specific applications.
产品使用（Use）: ：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件: ：Blue ice
