抗人EGFR(EGFR.1)抗体-超低内毒素
货号：ICH1021UL-5mg
品牌：ichorbio
产品特性
Bulk Anti-Human EGFR (EGFR.1) Antibody - Ultra-Low Endotoxin is manufactured in an cGMP compliant facility.
内毒素: ≤ 0.5 EU/mg as determined by the LAL method
纯度: >98% by SDS-PAGE and HPLC
应用: Flow Cytometry, Immunocytochemistry, Immunofluorescence, IHC (Frozen), Immunoprecipitation, Neutralization, IP-Mass Spectrometry.
| 规格 | 价格 |
|---|---|
| 5mg | ￥咨询 |
产品咨询：info@biopcr.com
产品订购：sales@biopcr.com
技术支持：tech@biopcr.com
服务热线：400-860-6200
详细介绍
产品名称：抗人EGFR(EGFR.1)抗体-超低内毒素
别名：抗人EGFR抗体, Bulk Anti-Human EGFR (EGFR.1) Antibody - Ultra-Low Endotoxin, Anti-Human EGFR Antibody, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, ERBB, ERBB1, HER1
宿主：Mouse
应用：Flow Cytometry, Immunocytochemistry, Immunofluorescence, IHC (Frozen), Immunoprecipitation, Neutralization, IP-Mass Spectrometry
亚型：Mouse IgG2b Kappa
克隆：EGFR.1
浓度：1.0 - 5.0 mg/ml
免疫原：A431 cultured cells
反应性：Human
特异性：Anti-EGFR In Vivo Antibody - Ultra Low Endotoxin (EGFR.1) recognizes an epitope on Human EGFR
存储溶液：0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
储存条件：anti-EGFR In Vivo Antibody - Ultra Low Endotoxin (EGFR.1) is stable when stored at 2-8°C. Do not freeze.
推荐同型对照（Isotype Control）：Mouse IgG2b Isotype Control for In Vivo - Ultra Low Endotoxin [MPC-11] (ICH2250UL)
推荐缓冲液（Buffer）：体内抗体缓冲液pH5.0； 体内抗体缓冲液pH7.4； 体内抗体缓冲液pH8.0
靶点（Target）: EGFR
UniProt: ：P00533
纯化方法（Purification method）: This monoclonal antibody was purified using Protein A
背景资料（Background）: ：The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer. EGFR (epidermal growth factor receptor) exists on the cell surface and is activated by binding of its specific ligands, including epidermal growth factor and transforming growth factor A (TGFA) (note, a full list of the ligands able to activate EGFR and other members of the ErbB family is given in the ErbB article). ErbB2 has no known direct activating ligand, and may be in an activated state constitutively or become active upon heterodimerization with other family members such as EGFR. Upon activation by its growth factor ligands, EGFR undergoes a transition from an inactive monomeric form to an active homodimer - although there is some evidence that preformed inactive dimers may also exist before ligand binding. In addition to forming homodimers after ligand binding, EGFR may pair with another member of the ErbB receptor family, such as ErbB2/Her2/neu, to create an activated heterodimer. There is also evidence to suggest that clusters of activated EGFRs form, although it remains unclear whether this clustering is important for activation itself or occurs subsequent to activation of individual dimers.
纯度（Purity）: ：>98% by SDS-PAGE and HPLC
内毒素（Endotoxin）: ：≤ 0.5 EU/mg as determined by the LAL method
聚集（Aggregation）: ：Aggregation level ≤ 1%
IMPACT病原体检测（IMPACT Pathogen Test）：We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our mouse antibodies are tested for: Mycoplasma spp.
Mycoplasma pulmonis
Sendai virus
Mouse hepatitis virus
Pneumonia virus of mice
Minute virus of mice
Mouse parvovirus (MPV1-5)
Theiler's murine encephalomyelitis virus
Murine norovirus
Reovirus 3
Mouse rotavirus
Ectromelia virus
Lymphocytic choriomeningitis virus
Polyoma virus
Lactate dehydrogenase-elevating virus
Mouse adenovirus (MAD1, MAD2)
Mouse cytomegalovirus
K virus
Mouse thymic virus
Hantaan virus
Corynebacterium bovis
Corynebacterium spp. (HAC2)
应用说明（Application Notes）: ：Each investigator should determine their own optimal working dilution for specific applications.
产品使用（Use）: ：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件: ：Blue ice
返回列表
推荐缓冲液（Buffer）：体内抗体缓冲液pH5.0； 体内抗体缓冲液pH7.4； 体内抗体缓冲液pH8.0
靶点（Target）: EGFR
UniProt: ：P00533
纯化方法（Purification method）: This monoclonal antibody was purified using Protein A
背景资料（Background）: ：The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer. EGFR (epidermal growth factor receptor) exists on the cell surface and is activated by binding of its specific ligands, including epidermal growth factor and transforming growth factor A (TGFA) (note, a full list of the ligands able to activate EGFR and other members of the ErbB family is given in the ErbB article). ErbB2 has no known direct activating ligand, and may be in an activated state constitutively or become active upon heterodimerization with other family members such as EGFR. Upon activation by its growth factor ligands, EGFR undergoes a transition from an inactive monomeric form to an active homodimer - although there is some evidence that preformed inactive dimers may also exist before ligand binding. In addition to forming homodimers after ligand binding, EGFR may pair with another member of the ErbB receptor family, such as ErbB2/Her2/neu, to create an activated heterodimer. There is also evidence to suggest that clusters of activated EGFRs form, although it remains unclear whether this clustering is important for activation itself or occurs subsequent to activation of individual dimers.
纯度（Purity）: ：>98% by SDS-PAGE and HPLC
内毒素（Endotoxin）: ：≤ 0.5 EU/mg as determined by the LAL method
聚集（Aggregation）: ：Aggregation level ≤ 1%
IMPACT病原体检测（IMPACT Pathogen Test）：We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our mouse antibodies are tested for: Mycoplasma spp.
Mycoplasma pulmonis
Sendai virus
Mouse hepatitis virus
Pneumonia virus of mice
Minute virus of mice
Mouse parvovirus (MPV1-5)
Theiler's murine encephalomyelitis virus
Murine norovirus
Reovirus 3
Mouse rotavirus
Ectromelia virus
Lymphocytic choriomeningitis virus
Polyoma virus
Lactate dehydrogenase-elevating virus
Mouse adenovirus (MAD1, MAD2)
Mouse cytomegalovirus
K virus
Mouse thymic virus
Hantaan virus
Corynebacterium bovis
Corynebacterium spp. (HAC2)
应用说明（Application Notes）: ：Each investigator should determine their own optimal working dilution for specific applications.
产品使用（Use）: ：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件: ：Blue ice
