抗人CD119(GIR 208)抗体
货号:ICH1028-25mg
品牌:ichorbio
产品特性
Bulk Anti-Human CD119 (GIR 208) Antibody is manufactured in an cGMP compliant facility.
内毒素: ≤ 1.0 EU/mg as determined by the LAL method
纯度: >95% by SDS-PAGE and HPLC
应用: Immunoprecipitation, Western Blot, ELISA, Neutralization, Flow Cytometry.
规格 | 价格 |
---|---|
25mg | ¥咨询 |
产品咨询:info@biopcr.com
产品订购:sales@biopcr.com
技术支持:tech@biopcr.com
服务热线:400-860-6200
详细介绍
产品名称:抗人CD119(GIR 208)抗体
别名:抗人CD119抗体, Bulk Anti-Human CD119 (GIR 208) Antibody, Anti-Human CD119 Antibody, Interferon gamma receptor 1, IFN-gamma receptor 1, IFN-gamma-R1, CDw119, Interferon gamma receptor alpha-chain2, IFN-gamma-R-alpha
宿主:Mouse
应用:Immunoprecipitation, Western Blot, ELISA, Neutralization, Flow Cytometry
亚型:Mouse IgG1
克隆:GIR 208
浓度:1.0 - 5.0 mg/ml
免疫原:Human IFN-gamma R alpha, Purified from human placenta
反应性:Human
特异性:Anti-CD119 In Vivo Antibody - Low Endotoxin (GIR 208) recognizes Human IFN gamma R alpha
存储溶液:0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
储存条件:anti-CD119 In Vivo Antibody - Low Endotoxin (GIR 208) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
推荐同型对照(Isotype Control):Mouse IgG1 Isotype Control for In Vivo - Low Endotoxin [HKSP] (ICH2247)
推荐缓冲液(Buffer):体内抗体缓冲液pH5.0; 体内抗体缓冲液pH7.4; 体内抗体缓冲液pH8.0
靶点(Target): CD119
UniProt: :P15260
纯化方法(Purification method): This monoclonal antibody was purified using Protein A
抗原分布(Antigen Distribution):The IFN-gamma receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.
背景资料(Background): :Interferon-gamma (IFN-gamma) exerts its biologic effects by interacting with a single high affinity receptor, IFN-gamma receptor. This receptor is present on almost all cell types except mature erythrocytes. The IFN-gamma receptor consists of two polypeptide chains alpha and beta and requires association of JAK1, JAK2 and Stat1 for IFN-gamma signal transduction. In signal transduction, IFN-gamma induces tyrosine phosphorylation of IFN-gamma receptor alpha (IFNGR1) leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-gamma induced gene transcription. The IFN-gamma receptor is structurally related to the recently cloned IL-10 receptor. GIR 208 binds IFNGR1 and blocks binding of IFN-gamma to the receptor.
纯度(Purity): :>95% by SDS-PAGE and HPLC
内毒素(Endotoxin): :≤ 1.0 EU/mg as determined by the LAL method
聚集(Aggregation): :Aggregation level ≤ 5%
应用说明(Application Notes): :Each investigator should determine their own optimal working dilution for specific applications.
产品使用(Use): :Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件: :Blue ice
返回列表
推荐缓冲液(Buffer):体内抗体缓冲液pH5.0; 体内抗体缓冲液pH7.4; 体内抗体缓冲液pH8.0
靶点(Target): CD119
UniProt: :P15260
纯化方法(Purification method): This monoclonal antibody was purified using Protein A
抗原分布(Antigen Distribution):The IFN-gamma receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.
背景资料(Background): :Interferon-gamma (IFN-gamma) exerts its biologic effects by interacting with a single high affinity receptor, IFN-gamma receptor. This receptor is present on almost all cell types except mature erythrocytes. The IFN-gamma receptor consists of two polypeptide chains alpha and beta and requires association of JAK1, JAK2 and Stat1 for IFN-gamma signal transduction. In signal transduction, IFN-gamma induces tyrosine phosphorylation of IFN-gamma receptor alpha (IFNGR1) leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-gamma induced gene transcription. The IFN-gamma receptor is structurally related to the recently cloned IL-10 receptor. GIR 208 binds IFNGR1 and blocks binding of IFN-gamma to the receptor.
纯度(Purity): :>95% by SDS-PAGE and HPLC
内毒素(Endotoxin): :≤ 1.0 EU/mg as determined by the LAL method
聚集(Aggregation): :Aggregation level ≤ 5%
应用说明(Application Notes): :Each investigator should determine their own optimal working dilution for specific applications.
产品使用(Use): :Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件: :Blue ice