抗人CD119(GIR 208)抗体-超低内毒素
货号：ICH1028UL-100mg
品牌：ichorbio
产品特性
Bulk Anti-Human CD119 (GIR 208) Antibody - Ultra-Low Endotoxin is manufactured in an cGMP compliant facility.
内毒素: ≤ 0.5 EU/mg as determined by the LAL method
纯度: >98% by SDS-PAGE and HPLC
应用: Immunoprecipitation, Western Blot, Blocking, Functional Assays.
| 规格 | 价格 |
|---|---|
| 100mg | ￥咨询 |
产品咨询：info@biopcr.com
产品订购：sales@biopcr.com
技术支持：tech@biopcr.com
服务热线：400-860-6200
详细介绍
产品名称：抗人CD119(GIR 208)抗体-超低内毒素
别名：抗人CD119抗体, Bulk Anti-Human CD119 (GIR 208) Antibody - Ultra-Low Endotoxin, Anti-Human CD119 Antibody, Interferon gamma receptor 1, IFN-gamma receptor 1, IFN-gamma-R1, CDw119, Interferon gamma receptor alpha-chain2, IFN-gamma-R-alpha
宿主：Mouse
应用：Immunoprecipitation, Western Blot, Blocking, Functional Assays
亚型：Mouse IgG1
克隆：GIR 208
浓度：1.0 - 5.0 mg/ml
免疫原：Human IFN-gamma R alpha, Purified from human placenta
反应性：Human
特异性：Anti-CD119 In Vivo Antibody - Ultra Low Endotoxin (GIR 208) recognizes Human IFN gamma R alpha
存储溶液：0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
储存条件：anti-CD119 In Vivo Antibody - Ultra Low Endotoxin (GIR 208) is stable when stored at 2-8°C. For long term storage we recommended to store at -80°C.
推荐同型对照（Isotype Control）：Mouse IgG1 Isotype Control for In Vivo - Ultra Low Endotoxin [HKSP] (ICH2247UL)
推荐缓冲液（Buffer）：体内抗体缓冲液pH5.0； 体内抗体缓冲液pH7.4； 体内抗体缓冲液pH8.0
靶点（Target）: CD119
UniProt: ：P15260
纯化方法（Purification method）: This monoclonal antibody was purified using Protein A
抗原分布（Antigen Distribution）：The IFN-gamma receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.
背景资料（Background）: ：Interferon-gamma (IFN-gamma) exerts its biologic effects by interacting with a single high affinity receptor, IFN-gamma receptor. This receptor is present on almost all cell types except mature erythrocytes. The IFN-gamma receptor consists of two polypeptide chains alpha and beta and requires association of JAK1, JAK2 and Stat1 for IFN-gamma signal transduction. In signal transduction, IFN-gamma induces tyrosine phosphorylation of IFN-gamma receptor alpha (IFNGR1) leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-gamma induced gene transcription. The IFN-gamma receptor is structurally related to the recently cloned IL-10 receptor. GIR 208 binds IFNGR1 and blocks binding of IFN-gamma to the receptor.
纯度（Purity）: ：>98% by SDS-PAGE and HPLC
内毒素（Endotoxin）: ：≤ 0.5 EU/mg as determined by the LAL method
聚集（Aggregation）: ：Aggregation level ≤ 1%
IMPACT病原体检测（IMPACT Pathogen Test）：We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our mouse antibodies are tested for: Mycoplasma spp.
Mycoplasma pulmonis
Sendai virus
Mouse hepatitis virus
Pneumonia virus of mice
Minute virus of mice
Mouse parvovirus (MPV1-5)
Theiler's murine encephalomyelitis virus
Murine norovirus
Reovirus 3
Mouse rotavirus
Ectromelia virus
Lymphocytic choriomeningitis virus
Polyoma virus
Lactate dehydrogenase-elevating virus
Mouse adenovirus (MAD1, MAD2)
Mouse cytomegalovirus
K virus
Mouse thymic virus
Hantaan virus
Corynebacterium bovis
Corynebacterium spp. (HAC2)
应用说明（Application Notes）: ：Functional Assay: Clone GIR-208 can be used as an isotype with Clone MAR1-5A3 (Anti-Mouse IFNAR1) Each investigator should determine their own optimal working dilution for specific applications.
产品使用（Use）: ：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件: ：Blue ice
返回列表
推荐缓冲液（Buffer）：体内抗体缓冲液pH5.0； 体内抗体缓冲液pH7.4； 体内抗体缓冲液pH8.0
靶点（Target）: CD119
UniProt: ：P15260
纯化方法（Purification method）: This monoclonal antibody was purified using Protein A
抗原分布（Antigen Distribution）：The IFN-gamma receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.
背景资料（Background）: ：Interferon-gamma (IFN-gamma) exerts its biologic effects by interacting with a single high affinity receptor, IFN-gamma receptor. This receptor is present on almost all cell types except mature erythrocytes. The IFN-gamma receptor consists of two polypeptide chains alpha and beta and requires association of JAK1, JAK2 and Stat1 for IFN-gamma signal transduction. In signal transduction, IFN-gamma induces tyrosine phosphorylation of IFN-gamma receptor alpha (IFNGR1) leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-gamma induced gene transcription. The IFN-gamma receptor is structurally related to the recently cloned IL-10 receptor. GIR 208 binds IFNGR1 and blocks binding of IFN-gamma to the receptor.
纯度（Purity）: ：>98% by SDS-PAGE and HPLC
内毒素（Endotoxin）: ：≤ 0.5 EU/mg as determined by the LAL method
聚集（Aggregation）: ：Aggregation level ≤ 1%
IMPACT病原体检测（IMPACT Pathogen Test）：We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our mouse antibodies are tested for: Mycoplasma spp.
Mycoplasma pulmonis
Sendai virus
Mouse hepatitis virus
Pneumonia virus of mice
Minute virus of mice
Mouse parvovirus (MPV1-5)
Theiler's murine encephalomyelitis virus
Murine norovirus
Reovirus 3
Mouse rotavirus
Ectromelia virus
Lymphocytic choriomeningitis virus
Polyoma virus
Lactate dehydrogenase-elevating virus
Mouse adenovirus (MAD1, MAD2)
Mouse cytomegalovirus
K virus
Mouse thymic virus
Hantaan virus
Corynebacterium bovis
Corynebacterium spp. (HAC2)
应用说明（Application Notes）: ：Functional Assay: Clone GIR-208 can be used as an isotype with Clone MAR1-5A3 (Anti-Mouse IFNAR1) Each investigator should determine their own optimal working dilution for specific applications.
产品使用（Use）: ：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件: ：Blue ice
