Adalimumab生物类似药-科研级
货号:ICH4001-1g
品牌:ichorbio
产品特性
英文名称: Adalimumab Biosimilar - Research Grade
内毒素水平≤ 1.0 EU/mg
纯度:>95% by SDS-PAGE and HPLC
特异性:Detects human TNF alpha. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Adalimumab.
规格 | 价格 |
---|---|
1g | ¥咨询 |
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服务热线:400-860-6200
详细介绍
产品名称:Adalimumab生物类似药-科研级
别名:Adalimumab Biosimilar-Research Grade, Cachectin, TNFa, Tumor necrosis factor ligand superfamily member 2, Tnfsf2
宿主:Humanized
亚型:Human IgG1 Kappa
浓度:1.0 - 5.0 mg/ml
反应性:Human
特异性:Detects human TNF alpha. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Adalimumab.
存储溶液:Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
储存条件:Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
推荐同型对照(Isotype Control):Bulk Human IgG1 Isotype Control (IB1) [ICH2254]
推荐缓冲液(Buffer):体内抗体缓冲液pH5.0; 体内抗体缓冲液pH7.4; 体内抗体缓冲液pH8.0
靶点(Target): TNF alpha
UniProt: :P01375
纯化方法(Purification method): : This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
抗原分布(Antigen Distribution):Activated monocytes, neutrophils, macrophages, T cells, B cells, NK cells, LAK cells
背景资料(Background):Adalimumab biosimilar is a recombinant human IgG1 monoclonal antibody specific for human tumor necrosis factor (TNF),was created using phage display technology resulting in an antibody with human derived heavy and light chain variable regions and human IgG1:k constant regions. Adalimumab biosimilar is produced by recombinant DNA technology in a mammalian cell (Chinese Hamster Ovary) expression system and is purified by a process that includes specific viral inactivation and removal steps. It consists of 1330 amino acids and has a molecular weight of approximately 148 kilodaltons.
内毒素(Endotoxin):≤ 1.0 EU/mg as determined by the LAL method
纯度(Purity):>95% by SDS-PAGE and HPLC
产品使用(Use):Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件:Blue ice
返回列表
推荐缓冲液(Buffer):体内抗体缓冲液pH5.0; 体内抗体缓冲液pH7.4; 体内抗体缓冲液pH8.0
靶点(Target): TNF alpha
UniProt: :P01375
纯化方法(Purification method): : This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
抗原分布(Antigen Distribution):Activated monocytes, neutrophils, macrophages, T cells, B cells, NK cells, LAK cells
背景资料(Background):Adalimumab biosimilar is a recombinant human IgG1 monoclonal antibody specific for human tumor necrosis factor (TNF),was created using phage display technology resulting in an antibody with human derived heavy and light chain variable regions and human IgG1:k constant regions. Adalimumab biosimilar is produced by recombinant DNA technology in a mammalian cell (Chinese Hamster Ovary) expression system and is purified by a process that includes specific viral inactivation and removal steps. It consists of 1330 amino acids and has a molecular weight of approximately 148 kilodaltons.
内毒素(Endotoxin):≤ 1.0 EU/mg as determined by the LAL method
纯度(Purity):>95% by SDS-PAGE and HPLC
产品使用(Use):Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件:Blue ice