Murine Anti-Protein C抗体(GMA-054)
货号:GMA-054
品牌:Greenmoab
产品特性
Specificity:activation region of Protein C
Immunogen:Human Protein C
Application:ELISA,Immunoblotting and Inhibition
规格 | 价格 |
---|---|
0.1 mg | ¥咨询 |
0.5 mg | ¥咨询 |
产品咨询:info@biopcr.com
产品订购:sales@biopcr.com
技术支持:tech@biopcr.com
服务热线:400-860-6200
详细介绍
产品名称:Murine Anti-Protein C抗体(GMA-054)
别名:Murine Anti-Protein C Antibody;Murine Anti-Protein C Monoclonal Antibody;Murine Anti-Protein C单克隆抗体;PC抗体;Murine Anti-Protein C抗体;小鼠抗蛋白C抗体;小鼠抗蛋白C单克隆抗体;Mouse Anti-Protein C Antibody
克隆号(Clone):GMA-054
背景介绍(Background):
Thrombin, in the presence of thrombomodulin, cleaves protein C giving the active protease activated protein C (APC). APC plays a regulatory role in coagulation by functioning as an anticoagulant by proteolytic inactivation of Factors V (Va) and VIII (VIIIa). Protein C (Mr 62,000) consists of a heavy chain (Mr 41,000) disulfide bonded to a Gla-containing light chain (Mr 21,000) which contains two EGF domains. GMA-054 is calcium dependent, and recognizes the activation region of Protein C. It can be used in western blot and ELISA applications. GMA-054 does not recognize activated Protein C and inhibits activation of Protein C by thrombin-thrombomodulin.
种属反应性(Species Reactivity): Baboon, Canine, Human, Pig
来源(Source): Murine
特异性(Specificity): activation region of Protein C
免疫原(Immunogen): Human Protein C
亚型(Isotype): IgG1
应用(Application):
ELISA: Binds immobilized human protein C only in the presence of calcium.
Immunoblotting: Binds protein C under reduced and non-reduced conditions.
Inhibition: Inhibits activation of Protein C by thrombin-thrombomodulin.
储存(Storage):Aliquot and store at -20℃ for prolonged periods. Avoid freeze-thaw cycles. Alternatively, add 0.02% (w/v) sodium azide and store at 4℃.
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背景介绍(Background):
Thrombin, in the presence of thrombomodulin, cleaves protein C giving the active protease activated protein C (APC). APC plays a regulatory role in coagulation by functioning as an anticoagulant by proteolytic inactivation of Factors V (Va) and VIII (VIIIa). Protein C (Mr 62,000) consists of a heavy chain (Mr 41,000) disulfide bonded to a Gla-containing light chain (Mr 21,000) which contains two EGF domains. GMA-054 is calcium dependent, and recognizes the activation region of Protein C. It can be used in western blot and ELISA applications. GMA-054 does not recognize activated Protein C and inhibits activation of Protein C by thrombin-thrombomodulin.
种属反应性(Species Reactivity): Baboon, Canine, Human, Pig
来源(Source): Murine
特异性(Specificity): activation region of Protein C
免疫原(Immunogen): Human Protein C
亚型(Isotype): IgG1
应用(Application):
ELISA: Binds immobilized human protein C only in the presence of calcium.
Immunoblotting: Binds protein C under reduced and non-reduced conditions.
Inhibition: Inhibits activation of Protein C by thrombin-thrombomodulin.
储存(Storage):Aliquot and store at -20℃ for prolonged periods. Avoid freeze-thaw cycles. Alternatively, add 0.02% (w/v) sodium azide and store at 4℃.