Murine Anti-Factor XI抗体(GMA-070)
货号:GMA-070
品牌:Greenmoab
产品特性
Specificity:Factor XI/XIa
Immunogen:Human Factor XI
Application:ELISA and Immunoblotting
规格 | 价格 |
---|---|
0.1 mg | ¥咨询 |
0.5 mg | ¥咨询 |
产品咨询:info@biopcr.com
产品订购:sales@biopcr.com
技术支持:tech@biopcr.com
服务热线:400-860-6200
详细介绍
产品名称:Murine Anti-Factor XI抗体(GMA-070)
别名:Murine Anti-Factor XI Antibody;Murine Anti-Factor XI Monoclonal Antibody;Murine Anti-Factor XI单克隆抗体;FXI抗体;Murine Anti-Factor XI抗体;小鼠抗凝血因子XI抗体;小鼠抗凝血因子XI单克隆抗体;Mouse Anti-Factor XI Antibody
克隆号(Clone):GMA-070
背景介绍(Background):
Factor XI is a key player in the intrinsic blood coagulation pathway. It circulates in complex with high molecular weight kininogen. When activated by factor XIIa, thrombin or autoactivation, the activated form factor XIa contributes to both hemostasis and thrombosis by amplifying thrombin generation and fibrin formation leading to clot formation. Human factor XI has a molecular weight of 160 kDa, and is comprised of a disulfide-linked dimer, with each monomer containing four apple domains that form a ring around the base of the catalytic domain. GMA-070 (also known as 5F71) is suitable for ELISA, western blot and immunopurification1 applications.
种属反应性(Species Reactivity): Human
来源(Source): Murine
特异性(Specificity): Factor XI/XIa
免疫原(Immunogen): Human Factor XI
亚型(Isotype): IgG1
应用(Application):
ELISA: Binds human factor XI and human factor XIa.
Immunoblotting: Western blot detects factor XI and factor XIa under non-reduced conditions.
储存(Storage):Aliquot and store at -20℃ for prolonged periods. Avoid freeze-thaw cycles. Alternatively, add 0.02% (w/v) sodium azide and store at 4℃.
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背景介绍(Background):
Factor XI is a key player in the intrinsic blood coagulation pathway. It circulates in complex with high molecular weight kininogen. When activated by factor XIIa, thrombin or autoactivation, the activated form factor XIa contributes to both hemostasis and thrombosis by amplifying thrombin generation and fibrin formation leading to clot formation. Human factor XI has a molecular weight of 160 kDa, and is comprised of a disulfide-linked dimer, with each monomer containing four apple domains that form a ring around the base of the catalytic domain. GMA-070 (also known as 5F71) is suitable for ELISA, western blot and immunopurification1 applications.
种属反应性(Species Reactivity): Human
来源(Source): Murine
特异性(Specificity): Factor XI/XIa
免疫原(Immunogen): Human Factor XI
亚型(Isotype): IgG1
应用(Application):
ELISA: Binds human factor XI and human factor XIa.
Immunoblotting: Western blot detects factor XI and factor XIa under non-reduced conditions.
储存(Storage):Aliquot and store at -20℃ for prolonged periods. Avoid freeze-thaw cycles. Alternatively, add 0.02% (w/v) sodium azide and store at 4℃.