Murine Anti-Factor IX抗体(GMA-102)
货号：GMA-102
品牌：Greenmoab
产品特性
Specificity：Heavy chain of FIX/FIXa
Immunogen：Human Factor IX
Application：ELISA and Immunoblotting
| 规格 | 价格 |
|---|---|
| 0.1 mg | ￥咨询 |
| 0.5 mg | ￥咨询 |
产品咨询：info@biopcr.com
产品订购：sales@biopcr.com
技术支持：tech@biopcr.com
服务热线：400-860-6200
详细介绍
产品名称：Murine Anti-Factor IX抗体(GMA-102)
别名：Murine Anti-Factor IX Antibody；Murine Anti-Factor IX Monoclonal Antibody；Murine Anti-Factor IX单克隆抗体；小鼠抗Factor IX抗体；小鼠抗FIX抗体；Murine Anti-Factor IX抗体；小鼠抗凝血因子IX抗体；Mouse Anti-Factor IX Antibody；F9抗体
克隆号（Clone）：GMA-102
背景介绍（Background）：
Factor IX (FIX) is a vitamin K-dependent zymogen that plays an essential role in the coagulation cascade leading to thrombus formation. In the presence of calcium, activated Factor IX (FIXa) complexes with Factor VIIIa on phospholipid surfaces to create the tenase complex, which converts Factor X to its activated form. Defect or deficiencies in FIX lead to the X-linked recessive bleeding disorder hemophilia B. GMA-102 (also known as GMA-002) binds to FIX and detects the heavy chain of FIXa in both ELISA and Western blot format, and bound GMA-102 captures FIX by bio-layer interferometry.
种属反应性（Species Reactivity）: Human, Porcine
来源（Source）： Murine
特异性（Specificity）： Heavy chain of FIX/FIXa
免疫原（Immunogen）： Human Factor IX
亚型（Isotype）： IgG1
应用（Application）：
ELISA： Binds immobilized Human and Porcine FIX and Human IXa.
Immunoblotting： Western blot detects Human FIX and heavy chain of Human FIXa under reduced conditions.
Inhibition： Prolongs plasma clot time in APTT clotting assay.
BLI： KD=6 nM (kdis=4.6 x 10-3 sec-1) by bio-layer interferometry
储存（Storage）：Aliquot and store at -20℃ for prolonged periods. Avoid freeze-thaw cycles. Alternatively, add 0.02% (w/v) sodium azide and store at 4℃.
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背景介绍（Background）：
Factor IX (FIX) is a vitamin K-dependent zymogen that plays an essential role in the coagulation cascade leading to thrombus formation. In the presence of calcium, activated Factor IX (FIXa) complexes with Factor VIIIa on phospholipid surfaces to create the tenase complex, which converts Factor X to its activated form. Defect or deficiencies in FIX lead to the X-linked recessive bleeding disorder hemophilia B. GMA-102 (also known as GMA-002) binds to FIX and detects the heavy chain of FIXa in both ELISA and Western blot format, and bound GMA-102 captures FIX by bio-layer interferometry.
种属反应性（Species Reactivity）: Human, Porcine
来源（Source）： Murine
特异性（Specificity）： Heavy chain of FIX/FIXa
免疫原（Immunogen）： Human Factor IX
亚型（Isotype）： IgG1
应用（Application）：
ELISA： Binds immobilized Human and Porcine FIX and Human IXa.
Immunoblotting： Western blot detects Human FIX and heavy chain of Human FIXa under reduced conditions.
Inhibition： Prolongs plasma clot time in APTT clotting assay.
BLI： KD=6 nM (kdis=4.6 x 10-3 sec-1) by bio-layer interferometry
储存（Storage）：Aliquot and store at -20℃ for prolonged periods. Avoid freeze-thaw cycles. Alternatively, add 0.02% (w/v) sodium azide and store at 4℃.
