Murine Anti-Factor X抗体(GMA-529)
货号：GMA-529
品牌：Greenmoab
产品特性
Specificity：Factor X/Xa
Immunogen：Human Factor X
Application：ELISA,Immunoblotting and Inhibition
| 规格 | 价格 |
|---|---|
| 0.1 mg | ￥咨询 |
| 0.5 mg | ￥咨询 |
产品咨询：info@biopcr.com
产品订购：sales@biopcr.com
技术支持：tech@biopcr.com
服务热线：400-860-6200
详细介绍
产品名称：Murine Anti-Factor X抗体(GMA-529)
别名：Murine Anti-Factor X Antibody；Murine Anti-Factor X Monoclonal Antibody；Murine Anti-Factor X单克隆抗体；FX抗体；Murine Anti-Factor X抗体；小鼠抗Factor X抗体；小鼠抗凝血因子X抗体；Mouse Anti-Factor X Antibody；F10抗体
克隆号（Clone）：GMA-529
背景介绍（Background）：
Factor X (Mr 59,000) is a vitamin K-dependent plasma protein zymogen that plays a central role as the substrate for both the intrinsic (factor VIIa, tissue factor) and extrinsic (factor IXa, factor VIIIa) pathways. In the presence of cofactor factor Va, phospholipid, and Ca2+, activated factor X cleaves two peptide bonds in prothrombin to form thrombin. GMA-529 (also known as α-HFX-27) binds human factor X and Xa in solid-phase ELISA and Western blot. GMA-529 prolonged FX-dependent clotting time, and activated partial thromboplastin time of normal plasma, and showed inhibition of thrombin generation.1
种属反应性（Species Reactivity）: Human
来源（Source）： Murine
特异性（Specificity）： Factor X/Xa
免疫原（Immunogen）： Human Factor X
亚型（Isotype）： IgG1
应用（Application）：
ELISA： Binds immobilized human factor X and factor Xa. Does not bind mouse FX.
Immunoblotting： Binds human factor X and Xa under non-reduced conditions. Does not blot reduced FX/Xa.
Inhibition： Inhibits thrombin generation, prolongs clotting time.
储存（Storage）：Aliquot and store at -20℃ for prolonged periods. Avoid freeze-thaw cycles. Alternatively, add 0.02% (w/v) sodium azide and store at 4℃.
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背景介绍（Background）：
Factor X (Mr 59,000) is a vitamin K-dependent plasma protein zymogen that plays a central role as the substrate for both the intrinsic (factor VIIa, tissue factor) and extrinsic (factor IXa, factor VIIIa) pathways. In the presence of cofactor factor Va, phospholipid, and Ca2+, activated factor X cleaves two peptide bonds in prothrombin to form thrombin. GMA-529 (also known as α-HFX-27) binds human factor X and Xa in solid-phase ELISA and Western blot. GMA-529 prolonged FX-dependent clotting time, and activated partial thromboplastin time of normal plasma, and showed inhibition of thrombin generation.1
种属反应性（Species Reactivity）: Human
来源（Source）： Murine
特异性（Specificity）： Factor X/Xa
免疫原（Immunogen）： Human Factor X
亚型（Isotype）： IgG1
应用（Application）：
ELISA： Binds immobilized human factor X and factor Xa. Does not bind mouse FX.
Immunoblotting： Binds human factor X and Xa under non-reduced conditions. Does not blot reduced FX/Xa.
Inhibition： Inhibits thrombin generation, prolongs clotting time.
储存（Storage）：Aliquot and store at -20℃ for prolonged periods. Avoid freeze-thaw cycles. Alternatively, add 0.02% (w/v) sodium azide and store at 4℃.
