Murine Anti-Factor X抗体(GMA-560)
货号：GMA-560
品牌：Greenmoab
产品特性
Specificity：Factor X heavy chain
Immunogen：Bovine Factor X
Application：ELISA and Immunoblotting
| 规格 | 价格 |
|---|---|
| 0.1 mg | ￥咨询 |
| 0.5 mg | ￥咨询 |
产品咨询：info@biopcr.com
产品订购：sales@biopcr.com
技术支持：tech@biopcr.com
服务热线：400-860-6200
详细介绍
产品名称：Murine Anti-Factor X抗体(GMA-560)
别名：Murine Anti-Factor X Antibody；Murine Anti-Factor X Monoclonal Antibody；Murine Anti-Factor X单克隆抗体；Factor X抗体；Murine Anti-Factor X抗体；小鼠抗凝血因子X抗体；Mouse Anti-Factor X Antibody；F10抗体
克隆号（Clone）：GMA-560
背景介绍（Background）：
Bovine Factor X (Mr 55,000) is a vitamin K-dependent plasma protein zymogen that plays a central role as the substrate for both the intrinsic (factor VIIa, tissue factor) and extrinsic (factor IXa, factor VIIIa) pathways. In the presence of cofactor factor Va, phospholipid, and Ca2+, activated factor X cleaves two peptide bonds in prothrombin to form thrombin. GMA-560 (also known as α-BFX-2b) binds bovine FX and factor Xa in solid-phase ELISA and Western blot. GMA-560 is partially calcium-dependent, inhibits FX activity in human, bovine, porcine, rabbit, and canine plasma inhibits the conversion of prothrombin to thrombin and prevents inactivation of FXa by antithrombin III1. It can be used in the purification of factor X from plasma2,3 and blocks FXa-thrombomodulin interaction4.
种属反应性（Species Reactivity）: Human
来源（Source）： Murine
特异性（Specificity）： Factor X heavy chain
免疫原（Immunogen）： Bovine Factor X
亚型（Isotype）： IgG1
应用（Application）：
ELISA： Binds bovine and human factor X and Xa in presence of calcium.
Immunoblotting： Binds bovine factor X and factor Xa heavy chain under reduced and non-reduced conditions in presence of calcium.
储存（Storage）：Aliquot and store at -20℃ for prolonged periods. Avoid freeze-thaw cycles. Alternatively, add 0.02% (w/v) sodium azide and store at 4℃.
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背景介绍（Background）：
Bovine Factor X (Mr 55,000) is a vitamin K-dependent plasma protein zymogen that plays a central role as the substrate for both the intrinsic (factor VIIa, tissue factor) and extrinsic (factor IXa, factor VIIIa) pathways. In the presence of cofactor factor Va, phospholipid, and Ca2+, activated factor X cleaves two peptide bonds in prothrombin to form thrombin. GMA-560 (also known as α-BFX-2b) binds bovine FX and factor Xa in solid-phase ELISA and Western blot. GMA-560 is partially calcium-dependent, inhibits FX activity in human, bovine, porcine, rabbit, and canine plasma inhibits the conversion of prothrombin to thrombin and prevents inactivation of FXa by antithrombin III1. It can be used in the purification of factor X from plasma2,3 and blocks FXa-thrombomodulin interaction4.
种属反应性（Species Reactivity）: Human
来源（Source）： Murine
特异性（Specificity）： Factor X heavy chain
免疫原（Immunogen）： Bovine Factor X
亚型（Isotype）： IgG1
应用（Application）：
ELISA： Binds bovine and human factor X and Xa in presence of calcium.
Immunoblotting： Binds bovine factor X and factor Xa heavy chain under reduced and non-reduced conditions in presence of calcium.
储存（Storage）：Aliquot and store at -20℃ for prolonged periods. Avoid freeze-thaw cycles. Alternatively, add 0.02% (w/v) sodium azide and store at 4℃.
