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ATXN3抗体

货号:AB0089-200 品牌:SICGEN antibodies

产品特性

Application:WB
Purification:Epitope affinity purified
Reactivity:Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other
Immunogen:Purified recombinant peptide derived from within residues 120 aa to 250 aa of human ATXN3 produced in E. coli.
规格 价格
600 µg 咨询
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详细介绍

产品名称:ATXN3抗体
别名:Anti-ATXN3 Antibody;AT3 Antibody;ATX3 Antibody;ataxin-3 Antibody;Ataxin 3 Antibody;ataxin 3 variant h;autosomal dominant ataxin 3;ataxin 3 variant m;ataxin 3 variant ref;JOS;josephin;Machado-Joseph;Machado-Joseph disease protein 1;MJD;MJD1;SCA3;spinocerebellar ataxia 3;olivopontocerebellar ataxia 3;spinocerebellar ataxia type 3 protein antibody;Ataxin 3抗体;Ataxin-3抗体;ATXN3抗体.
SICGEN antibodies ATXN3抗体,Ataxin 3抗体,经验证适用于WB,众多文献引用。

描述(Description):
Goat polyclonal antibody to ATXN3. This protein appears to be a component of the ubiquitin proteasome system and has deubiquitinase activity. It may also have roles in neuroprotection, protein homeostasis maintenance, transcriptional and cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. The protein contains Qn repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease also known as spinocerebellar ataxia-3, an autosomal dominant neurologic disorder.

抗体浓度(Concentration):3 mg/ml

抗体类型(Antibody Type):一抗.

靶点名称(Target Name):Anti-ATXN3

Accession Number:ENSG00000066427

来源(Source):Goat

免疫原物种(Immunogen Species):Human

免疫原类型(Immunogen Type):Recombinant protein

免疫原(Immunogen):Purified recombinant peptide derived from within residues 120 aa to 250 aa of human ATXN3 produced in E. coli.

亚型(Isotype):IgG

克隆性(Clonality):Polyclonal

已验证反应物种(Confirmed Reactive Species): Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other

特异性细节(Specificity Detail):Detects levels of ATXN3 protein in transfected cells with GFP-ATXN3 and endogenous levels in U118, SH-SY5Y, At-T20 and hTERT cell lysates by Western blot. This Ab is similar to AB10089.

缓冲液(Buffer):PBS, 20% glycerol and 0.05% sodium azide

纯化方式(Purification):Epitope affinity purified

偶联(Conjugation):Unconjugated

RRID:AB_2333113

应用(Application):WB

稀释浓度(Dilution Concentration):WB:1:250-1:2,000

储存(Storage):Store at -20 ℃ for long-term storage. Store at 2-8 ℃ for up to one month.

[注意事项]:勃谱生物销售的ATXN3抗体仅用于研究用途。不可用于诊断、医疗或其他用途。
[NOTICE]: Our products are for RESEARCH USE ONLY. Not for diagnostic, medical or other use.
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