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花青素7.5单琥珀酰亚胺酯 [等同于 Cy7.5® NHS酯]

货号:168 品牌:AAT Bioquest

产品特性

Molecular weight:1343.73
用于标记肽、蛋白质和寡糖
规格 价格
1 mg 咨询
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详细介绍

产品名称:花青素7.5单琥珀酰亚胺酯 [等同于 Cy7.5® NHS酯]
别名:Cyanine 7.5 monosuccinimidyl ester;Cy7.5® NHS ester;Cy7.5 NHS ester;Cy7.5 NHS酯;花青素7.5琥珀酰亚胺酯
储存条件:冷冻(< -15 °C);避光保存
Cyanine dyes are widely utilized for labeling biological molecules, particularly peptides, proteins, and oligos, in fluorescence imaging and other fluorescence-based biochemical analyses. Among these, Cyanine 7.5 (Cy7.5) NHS ester is notable for its near-infrared (NIR) properties, exhibiting long-wave emission characteristics. The NHS ester (or succinimidyl ester) is favored for its efficient reaction with the primary amines of proteins (Lys), peptides, amine-modified oligonucleotides, and other amine-containing molecules. Cy7.5 NHS Ester allows for high molar ratios of labeling without significant self-quenching, leading to brighter NIR conjugates and improved detection sensitivity. These conjugates demonstrate pH insensitivity over a wide range of molar concentrations, ensuring consistent signal generation in imaging and flow cytometry applications. Moreover, the near-infrared emission of Cy7.5 enables deep tissue penetration, making it ideal for in vivo imaging and tracking distribution in organisms. AAT Bioquest offers cyanine dye NHS esters in triethylammonium salt form, which exhibit superior solubility in dimethyl sulfoxide (DMSO) and dimethylformamide (DMF) compared to potassium salt formulations offered by other vendors. The reactivity of the cyanine dye triethylammonium salts is equivalent to that of cyanine dye potassium salts, producing conjugates with identical properties.
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