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抗CD115(AFS98)体内抗体-超低内毒素

货号:ICH1068UL-5mg 品牌:ichorbio

产品特性

Anti-CD115 (AFS98) In Vivo Antibody - Ultra-Low Endotoxin is manufactured in an cGMP compliant facility.
内毒素: ≤ 0.5 EU/mg as determined by the LAL method
纯度: >98% by SDS-PAGE and HPLC
应用: Western Blot, Blocking, Functional Assays, Flow Cytometry.
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详细介绍

产品名称:抗CD115(AFS98)体内抗体-超低内毒素
别名:抗CD115体内抗体, 抗CD115抗体-超低内毒素, Anti-CD115 (AFS98) In Vivo Antibody - Ultra-Low Endotoxin, Anti-CD115 In Vivo Antibody ,Anti-CD115 Antibody - Ultra-Low Endotoxin, Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor (EC:2.7.10.1), CSF-1-R, CSF-1R, M-CSF-R, Proto-oncogene c-Fms, Csf1r, Csfmr, Fms
宿主:Rat
应用:Western Blot, Blocking, Functional Assays, Flow Cytometry
亚型:Rat IgG2a Kappa
克隆:AFS98
浓度:1.0 - 5.0 mg/ml
免疫原:Purified Recombinant Mouse M-CSFR
反应性:Mouse
特异性:Anti-CD115 In Vivo Antibody - Ultra Low Endotoxin (AFS98) recognizes an epitope on Mouse M-CSFR
存储溶液:0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
储存条件:anti-CD115 In Vivo Antibody - Ultra Low Endotoxin (AFS98) is stable when stored at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. and keep sterile.
推荐同型对照(Isotype Control):Rat IgG2a In Vivo Isotype Control - Ultra Low Endotoxin [1-1] (ICH2244UL)
推荐缓冲液(Buffer):体内抗体缓冲液pH5.0; 体内抗体缓冲液pH7.4; 体内抗体缓冲液pH8.0
靶点(Target): CD115
UniProt:P09581
纯化方法(Purification method): This monoclonal antibody was purified using Protein G
抗原分布(Antigen Distribution):Monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, osteoclasts
背景资料(Background):Macrophage colony-stimulating factor (M-CSF, also termed CSF-1) receptor is an integral membrane tyrosine kinase, expressed in monocytes (macrophages and their progenitors) and drives growth and development of this blood cell lineage. It also triggers growth and development of mononuclear phagocytes and placental trophoblasts. M-CSF receptor is present in osteoclasts both at mRNA and protein levels. When M-CSF ligand specifically binds to the M-CSF receptor on osteoclasts, it induces receptor dimerization, activation and autophosphorylation of cytoplasmic tyrosine residues M-CSF and its receptor present as candidate therapeutic targets in states of inflammatory bone erosion.
纯度(Purity):>98% by SDS-PAGE and HPLC
内毒素(Endotoxin):≤ 0.5 EU/mg as determined by the LAL method
聚集(Aggregation):Aggregation level ≤ 1%
IMPACT病原体检测(IMPACT Pathogen Test):We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our rat antibodies are tested for:
Mycoplasma spp
Mycoplasma pulmonis
Pneumonia virus of mice
Kilham's rat virus
Toolan's H1 virus
Rat parvovirus
Lymphocytic choriomeningitis virus
Rat cytomegalovirus
Sendai virus
Rat coronavirus
Sialodacryoadenitis virus
Rat minute virus
Seoul virus
Mouse adenovirus
Reovirus 3
Rat theilovirus
应用说明(Application Notes):Each investigator should determine their own optimal working dilution for specific applications.
产品使用(Use):Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件:Blue ice
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