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抗CTLA-4(9H10)体内抗体-低内毒素

货号:ICH1084-25mg 品牌:ichorbio

产品特性

Anti-CTLA-4 (9H10) In Vivo Antibody - Low Endotoxin is manufactured in an cGMP compliant facility.
内毒素: ≤ 1.0 EU/mg as determined by the LAL method
纯度: >95% by SDS-PAGE and HPLC
应用: Western Blot, Blocking, ELISA, Flow Cytometry.
规格 价格
25mg 咨询
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详细介绍

产品名称:抗CTLA-4(9H10)体内抗体-低内毒素
别名:抗CTLA-4体内抗体, 抗CTLA-4抗体-低内毒素, Anti-CTLA-4 (9H10) In Vivo Antibody - Low Endotoxin, Anti-CTLA-4 In Vivo Antibody, Anti-CTLA-4 Antibody - Low Endotoxin, Ctla4, Cytotoxic T-lymphocyte protein 4, CD152
宿主:Syrian Hamster
应用:Western Blot, Blocking, ELISA, Flow Cytometry
亚型:Syrian Hamster IgG
克隆:9H10
浓度:1.0 - 5.0 mg/ml
免疫原:Mouse CTLA-4-human IgG1 fusion protein
反应性:Mouse
特异性:Anti-CTLA-4 In Vivo Antibody - Low Endotoxin (9H10) recognizes an epitope on Mouse CTLA-4
存储溶液:0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
储存条件:anti-CTLA-4 In Vivo Antibody - Low Endotoxin (9H10) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
推荐缓冲液(Buffer):体内抗体缓冲液pH5.0; 体内抗体缓冲液pH7.4; 体内抗体缓冲液pH8.0
靶点(Target): CTLA-4
UniProt:P09793
纯化方法(Purification method): This monoclonal antibody was purified using Protein A
抗原分布(Antigen Distribution):Activated T cells
背景资料(Background):CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) also known as CD152, is a protein which is expressed on the surface of Helper T cells and plays an important regulatory role in the immune system. CTLA4 is a member of the immunoglobulin superfamily, expressed on the surface of Helper T cells. CTLA4 transmits an inhibitory signal to T cells. CTLA4 is potentially therapeutic in auto-immune diseases4, such as rheumatoid arthritis, HIV, autoimmune thyroid disease, multiple sclerosis and may also be useful during organ transplantation and cancer treatment. Clone 9H10 antibody has been shown to promote T cell co-stimulation by blocking CTLA4 binding, allowing for CD28 binding.
纯度(Purity):>95% by SDS-PAGE and HPLC
内毒素(Endotoxin):≤ 1.0 EU/mg as determined by the LAL method
聚集(Aggregation):Aggregation level ≤ 5%
应用说明(Application Notes):Each investigator should determine their own optimal working dilution for specific applications.
产品使用(Use):Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件:Blue ice
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