抗小鼠IFN Beta(MIB-5E9.1)体内抗体-低内毒素
货号:ICH1124-100mg
品牌:ichorbio
产品特性
Anti-Mouse IFN Beta (MIB-5E9.1) In Vivo Antibody - Low Endotoxin is manufactured in an cGMP compliant facility.
内毒素: ≤ 1.0 EU/mg as determined by the LAL method
纯度: >95% by SDS-PAGE and HPLC
应用: Western Blot, Blocking.
规格 | 价格 |
---|---|
100mg | ¥咨询 |
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产品订购:sales@biopcr.com
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详细介绍
产品名称:抗小鼠IFN Beta(MIB-5E9.1)体内抗体-低内毒素
别名:抗小鼠IFN Beta体内抗体, 抗小鼠IFN Beta抗体-低内毒素, Anti-Mouse IFN Beta (MIB-5E9.1) In Vivo Antibody - Low Endotoxin, Anti-Mouse IFN Beta In Vivo Antibody, Anti-Mouse IFN Beta Antibody - Low Endotoxin, IFN-b, IFN-beta, Type-1 interferon, Interferon beta
宿主:Armenian Hamster
应用:Western Blot, Blocking
亚型:Armenian Hamster IgG
克隆:MIB-5E9.1
浓度:1.0 mg/ml
反应性:Mouse
特异性:Anti-IFN beta In Vivo Antibody - Low Endotoxin (MIB-5E9.1) recognizes Mouse IFN beta
存储溶液:0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
储存条件:anti-IFN beta In Vivo Antibody - Low Endotoxin (MIB-5E9.1) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
推荐同型对照(Isotype Control):Armenian Hamster IgG Isotype Control for In Vivo - Low Endotoxin [PIP] (ICH2251)
推荐缓冲液(Buffer):体内抗体缓冲液pH5.0; 体内抗体缓冲液pH7.4; 体内抗体缓冲液pH8.0
靶点(Target): IFN beta
UniProt:P01575
纯化方法(Purification method): This monoclonal antibody was purified using Protein A
抗原分布(Antigen Distribution):Fibroblasts & epithelial cells
背景资料(Background):Interferons (IFN) consist of two classes. The type I IFN class consists of 20 highly similar IFN-alpha proteins and a single IFN-beta protein. The second class, type II IFN, consists of a single protein, IFN-gamma. IFN-alpha and IFN-beta signal through the same cell surface receptor IFNAR1 and have a similar range of biological activities including antiviral and antiproliferative activity. The type I IFNs also influence activation, growth and differentiation of T cells, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. IFN-beta has recently proven to be beneficial in patients with multiple sclerosis and could also be a potential therapy for rheumatoid arthritis. It is unclear what cellular mechanisms are involved in IFN-beta’s therapeutic effects, but they may be caused by a restoration of balance between pro- and anti-inflammatory cytokines.
纯度(Purity):>95% by SDS-PAGE and HPLC
内毒素(Endotoxin):≤ 1.0 EU/mg as determined by the LAL method
聚集(Aggregation):Aggregation level ≤ 5%
应用说明(Application Notes):Each investigator should determine their own optimal working dilution for specific applications.
产品使用(Use):Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件:Blue ice
返回列表
推荐缓冲液(Buffer):体内抗体缓冲液pH5.0; 体内抗体缓冲液pH7.4; 体内抗体缓冲液pH8.0
靶点(Target): IFN beta
UniProt:P01575
纯化方法(Purification method): This monoclonal antibody was purified using Protein A
抗原分布(Antigen Distribution):Fibroblasts & epithelial cells
背景资料(Background):Interferons (IFN) consist of two classes. The type I IFN class consists of 20 highly similar IFN-alpha proteins and a single IFN-beta protein. The second class, type II IFN, consists of a single protein, IFN-gamma. IFN-alpha and IFN-beta signal through the same cell surface receptor IFNAR1 and have a similar range of biological activities including antiviral and antiproliferative activity. The type I IFNs also influence activation, growth and differentiation of T cells, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. IFN-beta has recently proven to be beneficial in patients with multiple sclerosis and could also be a potential therapy for rheumatoid arthritis. It is unclear what cellular mechanisms are involved in IFN-beta’s therapeutic effects, but they may be caused by a restoration of balance between pro- and anti-inflammatory cytokines.
纯度(Purity):>95% by SDS-PAGE and HPLC
内毒素(Endotoxin):≤ 1.0 EU/mg as determined by the LAL method
聚集(Aggregation):Aggregation level ≤ 5%
应用说明(Application Notes):Each investigator should determine their own optimal working dilution for specific applications.
产品使用(Use):Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件:Blue ice