抗PD-1(RMP1-14)抗体-极低内毒素
货号：ICH1132EL-50mg
品牌：ichorbio
产品特性
Anti-PD-1 (RMP1-14) - Extremely Low Endotoxin is manufactured in an cGMP compliant facility.
内毒素: ≤ 0.05 EU/mg as determined by the LAL method
纯度: >95% by SDS-PAGE and HPLC
应用: Western Blot, Blocking, Flow Cytometry, Functional Assays.
| 规格 | 价格 |
|---|---|
| 50mg | ￥咨询 |
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产品订购：sales@biopcr.com
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详细介绍
产品名称：抗PD-1(RMP1-14)抗体-极低内毒素
别名：抗PD-1抗体-极低内毒素, Anti-PD-1 (RMP1-14) - Extremely Low Endotoxin, Anti-PD-1 - Extremely Low Endotoxin, Programmed cell death protein 1, Pdcd1, CD279
宿主：Rat
应用：Western Blot, Blocking, Flow Cytometry, Functional Assays
亚型：Rat IgG2a Kappa
克隆：RMP1-14
浓度：1.0 - 5.0 mg/ml
免疫原：Mouse PD-1 transfected BHK cells
反应性：Mouse
特异性：Anti-PD-1 In Vivo Antibody - Low Endotoxin (RMP1-14) recognizes an epitope on Mouse PD-1
存储溶液：0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
储存条件：anti-PD-1 In Vivo Antibody - Low Endotoxin (RMP1-14) is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -70oC.
推荐同型对照（Isotype Control）：Rat IgG2a In Vivo Isotype Control - Low Endotoxin [1-1] (ICH2244)
推荐缓冲液（Buffer）：体内抗体缓冲液pH5.0； 体内抗体缓冲液pH7.4； 体内抗体缓冲液pH8.0
靶点（Target）: PD-1
UniProt：Q02242
纯化方法（Purification method）: This monoclonal antibody was purified using Protein G
抗原分布（Antigen Distribution）：Subset of double negative thymocytes, activated T and B cells
背景资料（Background）：CD279, also known as programmed death-1 (PD-1) is a 50-55 kD immunoglobulin superfamily member. PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. This RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production.
纯度（Purity）：>95% by SDS-PAGE and HPLC
内毒素（Endotoxin）：≤ 0.05 EU/mg as determined by the LAL method
聚集（Aggregation）：Aggregation level ≤ 5%
应用说明（Application Notes）：Blocking: Clone RMP1-14 antibody has been shown to block the binding of both mouse PD-L1-Ig and mouse PD-L2-Ig to PD-1. For immune checkpoint antibodies 200 ug per mouse per injection is the standard dosage in the literature. For this anti-PD-1 (clone RMP1-14), we suggest to inject 200 ug/mouse ip generally on days 3, 6 and 9, post injection of tumor. Sometime up to six injections depending on the length of the experiment may be required. Each investigator should determine their own optimal working dilution for specific applications.
产品使用（Use）：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件：Blue ice
返回列表
推荐缓冲液（Buffer）：体内抗体缓冲液pH5.0； 体内抗体缓冲液pH7.4； 体内抗体缓冲液pH8.0
靶点（Target）: PD-1
UniProt：Q02242
纯化方法（Purification method）: This monoclonal antibody was purified using Protein G
抗原分布（Antigen Distribution）：Subset of double negative thymocytes, activated T and B cells
背景资料（Background）：CD279, also known as programmed death-1 (PD-1) is a 50-55 kD immunoglobulin superfamily member. PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. This RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production.
纯度（Purity）：>95% by SDS-PAGE and HPLC
内毒素（Endotoxin）：≤ 0.05 EU/mg as determined by the LAL method
聚集（Aggregation）：Aggregation level ≤ 5%
应用说明（Application Notes）：Blocking: Clone RMP1-14 antibody has been shown to block the binding of both mouse PD-L1-Ig and mouse PD-L2-Ig to PD-1. For immune checkpoint antibodies 200 ug per mouse per injection is the standard dosage in the literature. For this anti-PD-1 (clone RMP1-14), we suggest to inject 200 ug/mouse ip generally on days 3, 6 and 9, post injection of tumor. Sometime up to six injections depending on the length of the experiment may be required. Each investigator should determine their own optimal working dilution for specific applications.
产品使用（Use）：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件：Blue ice
