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抗小鼠IFN Alpha(TIF-3C5)体内抗体-超低内毒素

货号:ICH1135UL-25mg 品牌:ichorbio

产品特性

Anti-Mouse IFN Alpha (TIF-3C5) In Vivo Antibody - Ultra-Low Endotoxin is manufactured in an cGMP compliant facility.
内毒素: ≤ 0.5 EU/mg as determined by the LAL method
纯度: >98% by SDS-PAGE and HPLC
应用: Western Blot, Functional Assays.
规格 价格
25mg 咨询
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详细介绍

产品名称:抗小鼠IFN Alpha(TIF-3C5)体内抗体-超低内毒素
别名:抗小鼠IFN Alpha体内抗体, 抗小鼠IFN Alpha抗体-超低内毒素, Anti-Mouse IFN Alpha (TIF-3C5) In Vivo Antibody - Ultra-Low Endotoxin, Anti-Mouse IFN Alpha In Vivo Antibody, Anti-Mouse IFN Alpha Antibody - Ultra-Low Endotoxin, IFNa, interferon alpha
宿主:Armenian Hamster
应用:Western Blot, Functional Assays
亚型:Armenian Hamster IgG
克隆:TIF-3C5
浓度:≥ 2.0 mg/ml
反应性:Mouse
特异性:Anti-IFN alpha In Vivo Antibody - Ultra-Low Endotoxin (TIF-3C5) recognizes an epitope on Mouse IFNalpha and binds specifically to murine IFNa species (IFN-alpha-A, -1, -4, -5, -11. and -13) and does not bind murine murine IFNg or IFNb
存储溶液:0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
储存条件:anti-IFN alpha In Vivo Antibody - Ultra Low Endotoxin (TIF-3C5) is stable when stored at 2-8°C. For long-term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
推荐同型对照(Isotype Control):Armenian Hamster IgG Isotype Control for In Vivo - Ultra Low Endotoxin [PIP] (ICH2251UL)
推荐缓冲液(Buffer):体内抗体缓冲液pH5.0; 体内抗体缓冲液pH7.4; 体内抗体缓冲液pH8.0
靶点(Target): IFN alpha
UniProt:P01572
纯化方法(Purification method): This monoclonal antibody was purified using Protein A
纯度(Purity):>98% by SDS-PAGE and HPLC
内毒素(Endotoxin):≤ 0.5 EU/mg as determined by the LAL method
聚集(Aggregation):Aggregation level ≤ 1%
IMPACT病原体检测(IMPACT Pathogen Test):We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our hamster antibodies are tested for: Mycoplasma spp
Mycoplasma pulmonis
Pneumonia virus of mice
Kilham's rat virus
Toolan's H1 virus
Hamster parvovirus
Lymphocytic choriomeningitis
Minute virus of mice
Theiler's murine encephalomyelitis virus
Sendai virus
Reovirus 3
Hantaan virus
应用说明(Application Notes):Functional Assay: In vitro activity of TIF-3C5 - inhibits IFNalpha -induced (IFNalpha-A, -1, -4, -5, -11 and 13) Stat1 phosphorylation in vitro. [TIF-1D6 does not block in vitro functional activity]. - blocks IFNA (IFNA-A, -1, -4, -5, -11 and 13) induction of MHC-I expression (H2-Kb) using L929 or fibrosarcoma cell lines in a dose dependent manner. - neutralizes IFNA-induced antiviral activity in vitro following infection of L929 cells with VSV. Functional activity of both recombinant (IFNalpha-A, -1, -4, -5, -11 and 13) and natural IFNalpha can be blocked with no neutralization of IFNgor IFNb. In vivo activity of TIF-3C5 - TIF-3C5 circulates with a half-life of 4 days - blockade of IFNa by TIF-3C5 increases the lethality of mice infected with West Nile Virus (WNV), similar to susceptibility of Irf7-/- mice. Each investigator should determine their own optimal working dilution for specific applications.
产品使用(Use):Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件:Blue ice
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