抗人Hepsin(2D5-1.9)抗体
货号:ICH1160-100mg
品牌:ichorbio
产品特性
Bulk Anti-Human Hepsin (2D5-1.9) Antibody is manufactured in an cGMP compliant facility.
内毒素: ≤ 1.0 EU/mg as determined by the LAL method
纯度: >95% by SDS-PAGE and HPLC
应用: ELISA, FC, WB.
规格 | 价格 |
---|---|
100mg | ¥咨询 |
产品咨询:info@biopcr.com
产品订购:sales@biopcr.com
技术支持:tech@biopcr.com
服务热线:400-860-6200
详细介绍
产品名称:抗人Hepsin(2D5-1.9)抗体
别名:抗人Hepsin抗体, Bulk, Anti-Human Hepsin (2D5-1.9) Antibody, Anti-Human Hepsin Antibody, Serine protease hepsin, hpn
宿主:Mouse
应用:ELISA, FC, WB
亚型:Mouse IgG2a Kappa
克隆:2D5-1.9
浓度:1mg/ml
免疫原:Human hepsin protein
反应性:Human
特异性:Clone 2D5 recognizes Human hepsin. It binds to a separate epitope than clone 3H10.1. These clones do not interfere with one another.
存储溶液:This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and azide free
储存条件:This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
推荐同型对照(Isotype Control):Mouse IgG2a In Vivo Isotype Control - Low Endotoxin [C1.18.4] (ICH2245)
推荐缓冲液(Buffer):体内抗体缓冲液pH5.0; 体内抗体缓冲液pH7.4; 体内抗体缓冲液pH8.0
靶点(Target): Hepsin
UniProt:P05981
纯化方法(Purification method): This monoclonal antibody was purified using Protein A
抗原分布(Antigen Distribution):Hepsin is expressed on the surface of epithelial cells including the liver, kidney, prostate, and thyroid in human tissues.
背景资料(Background):Hepsin is a type II transmembrane serine protease (TTSP) expressed on the surface of epithelial cells including the liver, kidney, prostate, and thyroid in human tissues. The physiological function of hepsin is unclear, although, In vitro studies have shown that hepsin activates blood clotting factors VII, XII, and IX, pro-urokinase (pro-uPA), and pro-hepatocyte growth factor (pro-HGF). The over-expression of hepsin has been implicated in several types of cancer, especially ovarian and prostate, which makes it an attractive diagnostic marker for cancers. Most notably, hepsin has been identified as one of the most highly induced genes in prostate cancer, and this over-expression is correlated with the cancer progression and metastasis. Furthermore anti-hepsin antibodies have been shown to inhibit the invasion of human prostate cancer cells.1
纯度(Purity):>95% by SDS-PAGE and HPLC
内毒素(Endotoxin):≤ 1.0 EU/mg as determined by the LAL method
聚集(Aggregation):Aggregation level ≤ 5%
应用说明(Application Notes):Each investigator should determine their own optimal working dilution for specific applications.
产品使用(Use):Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件:Blue ice
返回列表
推荐缓冲液(Buffer):体内抗体缓冲液pH5.0; 体内抗体缓冲液pH7.4; 体内抗体缓冲液pH8.0
靶点(Target): Hepsin
UniProt:P05981
纯化方法(Purification method): This monoclonal antibody was purified using Protein A
抗原分布(Antigen Distribution):Hepsin is expressed on the surface of epithelial cells including the liver, kidney, prostate, and thyroid in human tissues.
背景资料(Background):Hepsin is a type II transmembrane serine protease (TTSP) expressed on the surface of epithelial cells including the liver, kidney, prostate, and thyroid in human tissues. The physiological function of hepsin is unclear, although, In vitro studies have shown that hepsin activates blood clotting factors VII, XII, and IX, pro-urokinase (pro-uPA), and pro-hepatocyte growth factor (pro-HGF). The over-expression of hepsin has been implicated in several types of cancer, especially ovarian and prostate, which makes it an attractive diagnostic marker for cancers. Most notably, hepsin has been identified as one of the most highly induced genes in prostate cancer, and this over-expression is correlated with the cancer progression and metastasis. Furthermore anti-hepsin antibodies have been shown to inhibit the invasion of human prostate cancer cells.1
纯度(Purity):>95% by SDS-PAGE and HPLC
内毒素(Endotoxin):≤ 1.0 EU/mg as determined by the LAL method
聚集(Aggregation):Aggregation level ≤ 5%
应用说明(Application Notes):Each investigator should determine their own optimal working dilution for specific applications.
产品使用(Use):Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件:Blue ice