抗人CD195(HEK/1/85a/7a)抗体(CCR5)
货号：ICH1172-100mg
品牌：ichorbio
产品特性
Bulk Anti-Human CD195 (HEK/1/85a/7a) Antibody (CCR5) is manufactured in an cGMP compliant facility.
内毒素: <1.0 EU/mg as determined by the LAL method
纯度: ≥95% monomer by analytical SEC, >95% by SDS-PAGE
应用: Flow Cytometry, ImmunoCytochemistry.
| 规格 | 价格 |
|---|---|
| 100mg | ￥咨询 |
产品咨询：info@biopcr.com
产品订购：sales@biopcr.com
技术支持：tech@biopcr.com
服务热线：400-860-6200
详细介绍
产品名称：抗人CD195(HEK/1/85a/7a)抗体(CCR5)
别名：抗人CD195抗体, Bulk, Anti-Human CD195 (HEK/1/85a/7a) Antibody (CCR5), Anti-Human CD195 Antibody , C-C chemokine receptor type 5, CC-CKR-5, CCR-5, CHEMR13, HIV-1 fusion coreceptor, CD195
宿主：Rat
应用：Flow Cytometry, ImmunoCytochemistry
亚型：Rat IgG2b Kappa
克隆：HEK/1/85a/7a
浓度：≥ 5.0 mg/ml
免疫原：CHO cells transfected with full-length human CD195 (CCR5).
反应性：Human
特异性：Clone HEK/1/85a/7a recognizes an epitope on human CCR5
存储溶液：This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
储存条件：This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
推荐同型对照（Isotype Control）：Rat IgG2b In Vivo Isotype Control - Low Endotoxin [1-2] (ICH2243)
推荐缓冲液（Buffer）：体内抗体缓冲液pH5.0； 体内抗体缓冲液pH7.4； 体内抗体缓冲液pH8.0
靶点（Target）: CCR5
UniProt：P51681
纯化方法（Purification method）: This monoclonal antibody was purified using Protein G
抗原分布（Antigen Distribution）：CCR5 is expressed on memory T cells, macrophages, and immature dendritic cells (DCs)
背景资料（Background）：CCR5 antibody, HEK/1/85a/7a, recognizes C-C chemokine receptor type 5 (CCR5), also known as CD195, CC-CKR-5, CHEMR13, and HIV-1 fusion coreceptor. CCR5 is a 45 kDa seven-transmembrane G-protein-coupled receptor (GPCR). CCR5 is expressed on a subset of memory T cells, macrophages, and immature dendritic cells (DCs) and is upregulated by proinflammatory cytokines. CCR5 binds to inflammatory CC-chemokines, including CCL3 (macrophage inflammatory protein (MIP)-1α), CCL4 (MIP-1β), and RANTES, which increases intracellular calcium levels and results in cytoskeletal rearrangement and chemotactic cell migration. CCR5 is also the coreceptor for HIV-1 following binding of viral gp120 to CD44-7. The levels of CCR5 on cells influence the rate of entry of HIV-1, and patients with lower levels of CCR5 exhibit immunity against infection. CCR5 also contributes to other human diseases, including type I diabetes and cancer.
纯度（Purity）：≥95% monomer by analytical SEC, >95% by SDS-PAGE
内毒素（Endotoxin）：<1.0 EU/mg as determined by the LAL method
聚集（Aggregation）：Aggregation level ≤ 5%
应用说明（Application Notes）：The suggested concentration for this CD195 antibody for staining cells in flow cytometry is ≤ 1.0 μg per 10^6 cells in a volume of 100 μl. Titration of the reagent is recommended for optimal performance for each application.
产品使用（Use）：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件：Blue ice
返回列表
推荐缓冲液（Buffer）：体内抗体缓冲液pH5.0； 体内抗体缓冲液pH7.4； 体内抗体缓冲液pH8.0
靶点（Target）: CCR5
UniProt：P51681
纯化方法（Purification method）: This monoclonal antibody was purified using Protein G
抗原分布（Antigen Distribution）：CCR5 is expressed on memory T cells, macrophages, and immature dendritic cells (DCs)
背景资料（Background）：CCR5 antibody, HEK/1/85a/7a, recognizes C-C chemokine receptor type 5 (CCR5), also known as CD195, CC-CKR-5, CHEMR13, and HIV-1 fusion coreceptor. CCR5 is a 45 kDa seven-transmembrane G-protein-coupled receptor (GPCR). CCR5 is expressed on a subset of memory T cells, macrophages, and immature dendritic cells (DCs) and is upregulated by proinflammatory cytokines. CCR5 binds to inflammatory CC-chemokines, including CCL3 (macrophage inflammatory protein (MIP)-1α), CCL4 (MIP-1β), and RANTES, which increases intracellular calcium levels and results in cytoskeletal rearrangement and chemotactic cell migration. CCR5 is also the coreceptor for HIV-1 following binding of viral gp120 to CD44-7. The levels of CCR5 on cells influence the rate of entry of HIV-1, and patients with lower levels of CCR5 exhibit immunity against infection. CCR5 also contributes to other human diseases, including type I diabetes and cancer.
纯度（Purity）：≥95% monomer by analytical SEC, >95% by SDS-PAGE
内毒素（Endotoxin）：<1.0 EU/mg as determined by the LAL method
聚集（Aggregation）：Aggregation level ≤ 5%
应用说明（Application Notes）：The suggested concentration for this CD195 antibody for staining cells in flow cytometry is ≤ 1.0 μg per 10^6 cells in a volume of 100 μl. Titration of the reagent is recommended for optimal performance for each application.
产品使用（Use）：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件：Blue ice
