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鼠源化抗小鼠PD-1(RMP1-14)重组抗体LALAPG

货号:ICH1182LALAPG-25mg 品牌:ichorbio

产品特性

Murinized Anti-Mouse PD-1 (RMP1-14) Recombinant Antibody LALAPG is manufactured in an cGMP compliant facility.
内毒素: ≤ 1.0 EU/mg as determined by the LAL method
纯度: >95% by SDS-PAGE and HPLC
应用: Western Blot, Blocking, Flow Cytometry, Functional Assays.
规格 价格
25mg 咨询
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详细介绍

产品名称:鼠源化抗小鼠PD-1(RMP1-14)重组抗体LALAPG
别名:鼠源化抗小鼠PD-1重组抗体LALAPG, 鼠源化抗小鼠PD-1抗体LALAPG, Murinized, Anti-Mouse PD-1 (RMP1-14) Recombinant Antibody LALAPG, Murinized, Anti-Mouse PD-1 Recombinant Antibody LALAPG Murinized, Anti-Mouse PD-1 Antibody LALAPG, Programmed cell death protein 1, Pdcd1, CD279, Mouse, Anti-Mouse PD-1 (RMP1-14) Recombinant Antibody LALAPG
宿主:CHO
应用:Western Blot, Blocking, Flow Cytometry, Functional Assays
亚型:Mouse IgG2a
克隆:RMP1-14
浓度:1.0 - 5.0 mg/ml
免疫原:Mouse PD-1 transfected BHK cells
反应性:Mouse
特异性:Mouse anti-PD-1 antibody (RMP1-14) is a recombinant antibody where the original Rat IgG2a backbone of clone RMP1-14 has been changed to Mouse IgG2a. This antibody recognizes an epitope on Mouse PD-1
存储溶液:0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
储存条件:Mouse anti-mouse PD-1 antibody (RMP1-14) is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -70oC.
推荐同型对照(Isotype Control):Mouse IgG1 Isotype Control for In Vivo - Low Endotoxin [HKSP] (ICH2247)
推荐缓冲液(Buffer):体内抗体缓冲液pH5.0;体内抗体缓冲液pH7.4;体内抗体缓冲液pH8.0
靶点(Target): PD-1
UniProt:Q02242
纯化方法(Purification method): This monoclonal antibody was purified using Protein A
抗原分布(Antigen Distribution):Subset of double negative thymocytes, activated T and B cells
背景资料(Background):CD279, also known as programmed death-1 (PD-1) is a 50-55 kD immunoglobulin superfamily member. PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. This RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production.
纯度(Purity):>95% by SDS-PAGE and HPLC
内毒素(Endotoxin):≤ 1.0 EU/mg as determined by the LAL method
聚集(Aggregation):Aggregation level ≤ 5%
应用说明(Application Notes):Each investigator should determine their own optimal working dilution for specific applications.
产品使用(Use):Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件:Blue ice
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