抗人CD68(KP1)抗体
货号：ICH1190-5mg
品牌：ichorbio
产品特性
Bulk Anti-Human CD68 (KP1) Antibody is manufactured in an cGMP compliant facility.
内毒素: <1.0 EU/mg as determined by the LAL method
纯度: >95% by SDS-PAGE
应用: Blotting, Dot Blot, Electron Microscopy, Flow Cytrometry, Immunocytochemistry, ICFC, Immunohistochemistry, IHC-paraffin, Immunoprecipitation, Western Blotting.
| 规格 | 价格 |
|---|---|
| 5mg | ￥咨询 |
产品咨询：info@biopcr.com
产品订购：sales@biopcr.com
技术支持：tech@biopcr.com
服务热线：400-860-6200
详细介绍
产品名称：抗人CD68(KP1)抗体
别名：抗人CD68抗体, Bulk, Anti-Human CD68 (KP1) Antibody, Anti-Human CD68 Antibody, GP110, LAMP4, SCARD1
宿主：Mouse
应用：Blotting, Dot Blot, Electron Microscopy, Flow Cytrometry, Immunocytochemistry, ICFC, Immunohistochemistry, IHC-paraffin, Immunoprecipitation, Western Blotting
亚型：Mouse IgG1 Kappa
克隆：KP1
浓度：≥ 2.0 mg/ml
免疫原：Lysosomal fraction of human lung
反应性：Human
特异性：Anti-CD68 antibody (clone KP1) activity is directed against human CD68.
存储溶液：Sterile, preservative-free, solution in PBS. BSA and Azide free.
储存条件：This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
推荐同型对照（Isotype Control）：Mouse IgG1 Isotype Control for In Vivo - Low Endotoxin [HKSP] (ICH2247)
推荐缓冲液（Buffer）：体内抗体缓冲液pH5.0；体内抗体缓冲液pH7.4；体内抗体缓冲液pH8.0
靶点（Target）: CD68
纯化方法（Purification method）: This monoclonal antibody was purified using Protein A
抗原分布（Antigen Distribution）：CD68 is found in the cytoplasm of monocytes/macrophages, fibroblasts, human peripheral blood lymphocytes, neutrophil primary and mast cell granules, large granular lymphocytes, basophils, basal epithelial cell layers, renal glomeruli, myeloid cells, endothelial cells, retinal epithelial cells, osteoblasts, fibroblast-like cells from bone marrow, and a wide-range of lymphoid neoplasms. CD68 is predominantly located in lysosomal membranes, with a small amount on the cell surface. Additionally, CD68 can be expressed in most hematopoietic cell lines by phorbol-induced differentiation; soluble CD68 can also be found in serum and urine.
背景资料（Background）：KP1 was originally used as a pan-monocytic/macrophage marker against CD68; however, CD68 is not a macrophage specific antigen and KP1 is known to stain neutrophils and other non-macrophage-like cells. KP1 reacts against CD68 in a wide range of healthy and disease-associated (rheumatoid arthritis and osteoarthritis)5 tissues as well as a variety of neoplasms, tumor cell lines, and tumor-associated macrophages. KP1 detects a fixation-resistant epitope that is likely glycan-based which is shared by many cell types.KP1 was developed by immunizing Balb/c mice against a lysosomal fraction of human lung . Hybridoma supernatants derived from spleen cells were screened on cryostat human lung and tonsil sections as well as paraffin wax sections of lung tissue fixed in formol saline.
纯度（Purity）：>95% by SDS-PAGE
内毒素（Endotoxin）：<1.0 EU/mg as determined by the LAL method
聚集（Aggregation）：Aggregation level ≤ 5%
应用说明（Application Notes）：Each investigator should determine their own optimal working dilution for specific applications.
产品使用（Use）：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件：Blue ice
返回列表
推荐缓冲液（Buffer）：体内抗体缓冲液pH5.0；体内抗体缓冲液pH7.4；体内抗体缓冲液pH8.0
靶点（Target）: CD68
纯化方法（Purification method）: This monoclonal antibody was purified using Protein A
抗原分布（Antigen Distribution）：CD68 is found in the cytoplasm of monocytes/macrophages, fibroblasts, human peripheral blood lymphocytes, neutrophil primary and mast cell granules, large granular lymphocytes, basophils, basal epithelial cell layers, renal glomeruli, myeloid cells, endothelial cells, retinal epithelial cells, osteoblasts, fibroblast-like cells from bone marrow, and a wide-range of lymphoid neoplasms. CD68 is predominantly located in lysosomal membranes, with a small amount on the cell surface. Additionally, CD68 can be expressed in most hematopoietic cell lines by phorbol-induced differentiation; soluble CD68 can also be found in serum and urine.
背景资料（Background）：KP1 was originally used as a pan-monocytic/macrophage marker against CD68; however, CD68 is not a macrophage specific antigen and KP1 is known to stain neutrophils and other non-macrophage-like cells. KP1 reacts against CD68 in a wide range of healthy and disease-associated (rheumatoid arthritis and osteoarthritis)5 tissues as well as a variety of neoplasms, tumor cell lines, and tumor-associated macrophages. KP1 detects a fixation-resistant epitope that is likely glycan-based which is shared by many cell types.KP1 was developed by immunizing Balb/c mice against a lysosomal fraction of human lung . Hybridoma supernatants derived from spleen cells were screened on cryostat human lung and tonsil sections as well as paraffin wax sections of lung tissue fixed in formol saline.
纯度（Purity）：>95% by SDS-PAGE
内毒素（Endotoxin）：<1.0 EU/mg as determined by the LAL method
聚集（Aggregation）：Aggregation level ≤ 5%
应用说明（Application Notes）：Each investigator should determine their own optimal working dilution for specific applications.
产品使用（Use）：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件：Blue ice
