抗小鼠CD183(CXCR3-173)体内抗体-低内毒素
货号：ICH1201-5mg
品牌：ichorbio
产品特性
Anti-Mouse CD183 (CXCR3-173) In Vivo Antibody - Low Endotoxin is manufactured in an cGMP compliant facility.
内毒素: <1.0 EU/mg as determined by the LAL method
纯度: >95% by SDS-PAGE
应用: Flow Cytometry, Neutralization.
| 规格 | 价格 |
|---|---|
| 5mg | ￥咨询 |
产品咨询：info@biopcr.com
产品订购：sales@biopcr.com
技术支持：tech@biopcr.com
服务热线：400-860-6200
详细介绍
产品名称：抗小鼠CD183(CXCR3-173)体内抗体-低内毒素
别名：抗小鼠CD183体内抗体, 抗小鼠CD183抗体-低内毒素, Anti-Mouse CD183 (CXCR3-173) In Vivo Antibody - Low Endotoxin, Anti-Mouse CD183 In Vivo Antibody, Anti-Mouse CD183 Antibody - Low Endotoxin, CXCR3G, protein-coupled receptor 9 (GPR9), CKR-L2, IP10 receptor (IP10-R), Mig receptor (Mig-R ), CD183
宿主：Armenian Hamster
应用：Flow Cytometry, Neutralization
亚型：Armenian Hamster IgG
克隆：CXCR3-173
浓度：≥ 2.0 mg/ml
免疫原：CXCR3-173 was generated by immunizing Armenian hamsters with a peptide sequence unique to mouse CXCR3 which encompasses amino acids 1-37.
反应性：Mouse
特异性：CXCR3-173 activity is directed against murine CD183 (CXCR3).
存储溶液：Sterile, preservative-free, solution in PBS. BSA and Azide free.
储存条件：This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
推荐同型对照（Isotype Control）：Armenian Hamster IgG Isotype Control for In Vivo - Low Endotoxin [PIP] (ICH2251)
推荐缓冲液（Buffer）：体内抗体缓冲液pH5.0；体内抗体缓冲液pH7.4；体内抗体缓冲液pH8.0
靶点（Target）: CD183
纯化方法（Purification method）: This monoclonal antibody was purified using Protein A
抗原分布（Antigen Distribution）：CXCL3 is expressed on primary memory phenotype CD4+ and CD8+ T cells, naturally occurring CD4+CD25+ Foxp3+ regulatory T cells, natural killer (NK) T cells, and approximately 25% of NK cells. CXCR3-173 recognizes an epitope of CXCR3 expressed on the surface of activated mouse splenocytes.
背景资料（Background）：Hamsters were tested by ELISA for seropositivity against CXCR3 peptide and hybridomas were generated, screened by FACS, purified, and tested for: staining, CXCR3 blockade in vitro, and endotoxin levels. CXCR3-173 detects the native form of CXCR3, and therefore does not work in Western blotting.CXCR3-173 has potential use in immunotherapeutic approaches to inhibit transplant rejection and immune related diseases. In vitro, CXCR3-173 blocks chemotaxis in response to CXCL10 or CXCL11 but not CXCL9. In vivo, CXCR3-173 prolongs both cardiac and islet allograft survival in a manner further enhanced by rapamycin.
纯度（Purity）：>95% by SDS-PAGE
内毒素（Endotoxin）：<1.0 EU/mg as determined by the LAL method
聚集（Aggregation）：Aggregation level ≤ 5%
应用说明（Application Notes）：Each investigator should determine their own optimal working dilution for specific applications.
产品使用（Use）：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件：Blue ice
返回列表
推荐缓冲液（Buffer）：体内抗体缓冲液pH5.0；体内抗体缓冲液pH7.4；体内抗体缓冲液pH8.0
靶点（Target）: CD183
纯化方法（Purification method）: This monoclonal antibody was purified using Protein A
抗原分布（Antigen Distribution）：CXCL3 is expressed on primary memory phenotype CD4+ and CD8+ T cells, naturally occurring CD4+CD25+ Foxp3+ regulatory T cells, natural killer (NK) T cells, and approximately 25% of NK cells. CXCR3-173 recognizes an epitope of CXCR3 expressed on the surface of activated mouse splenocytes.
背景资料（Background）：Hamsters were tested by ELISA for seropositivity against CXCR3 peptide and hybridomas were generated, screened by FACS, purified, and tested for: staining, CXCR3 blockade in vitro, and endotoxin levels. CXCR3-173 detects the native form of CXCR3, and therefore does not work in Western blotting.CXCR3-173 has potential use in immunotherapeutic approaches to inhibit transplant rejection and immune related diseases. In vitro, CXCR3-173 blocks chemotaxis in response to CXCL10 or CXCL11 but not CXCL9. In vivo, CXCR3-173 prolongs both cardiac and islet allograft survival in a manner further enhanced by rapamycin.
纯度（Purity）：>95% by SDS-PAGE
内毒素（Endotoxin）：<1.0 EU/mg as determined by the LAL method
聚集（Aggregation）：Aggregation level ≤ 5%
应用说明（Application Notes）：Each investigator should determine their own optimal working dilution for specific applications.
产品使用（Use）：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件：Blue ice
