Eculizumab生物类似药-研究级
货号：ICH4005-500mg
品牌：ichorbio
产品特性
英文名称: Eculizumab Biosimilar - Research Grade
内毒素水平≤ 1.0 EU/mg
纯度：>95% by SDS-PAGE and HPLC
特异性：Detects human Complement protein C5. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Eculizumab.
| 规格 | 价格 |
|---|---|
| 500mg | ￥咨询 |
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详细介绍
产品名称：Eculizumab生物类似药-研究级
别名：Eculizumab Biosimilar-Research Grade, C5
宿主：Humanized
亚型：IgG2/4 kappa
浓度：1.0 - 5.0 mg/ml
反应性：Human
特异性：Detects human Complement protein C5. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Eculizumab.
存储溶液：Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
储存条件：Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
推荐缓冲液（Buffer）：体内抗体缓冲液pH5.0；体内抗体缓冲液pH7.4；体内抗体缓冲液pH8.0
靶点（Target）: Complement protein C5
UniProt：P01031
纯化方法（Purification method）： This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
背景资料（Background）：Eculizumab biosimilar is a recombinant humanized monoclonal IgG2/4κ antibody produced by Chinese hamster ovary cell culture and purified by standard bioprocess technology. Eculizumab biosimilar contains human constant regions from human IgG2 sequences and human IgG4 sequences and murine complementarity-determining regions grafted onto the human framework light- and heavy-chain variable regions. Eculizumab biosimilar is composed of two 448 amino acid heavy chains and two 214 amino acid light chains and has a molecular weight of approximately 148 kDa.
内毒素（Endotoxin）：≤ 1.0 EU/mg as determined by the LAL method
纯度（Purity）：>95% by SDS-PAGE and HPLC
产品使用（Use）：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件：Blue ice
返回列表
靶点（Target）: Complement protein C5
UniProt：P01031
纯化方法（Purification method）： This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
背景资料（Background）：Eculizumab biosimilar is a recombinant humanized monoclonal IgG2/4κ antibody produced by Chinese hamster ovary cell culture and purified by standard bioprocess technology. Eculizumab biosimilar contains human constant regions from human IgG2 sequences and human IgG4 sequences and murine complementarity-determining regions grafted onto the human framework light- and heavy-chain variable regions. Eculizumab biosimilar is composed of two 448 amino acid heavy chains and two 214 amino acid light chains and has a molecular weight of approximately 148 kDa.
内毒素（Endotoxin）：≤ 1.0 EU/mg as determined by the LAL method
纯度（Purity）：>95% by SDS-PAGE and HPLC
产品使用（Use）：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件：Blue ice
