Ado-Trastuzumab Emtansine生物类似药-科研级
货号：ICH4014-1g
品牌：ichorbio
产品特性
英文名称: Ado-Trastuzumab Emtansine Biosimilar - Research Grade
内毒素水平≤ 1.0 EU/mg
纯度：>95% by SDS-PAGE and HPLC
特异性：Detects human HER2. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Ado-trastuzumab emtansine.
| 规格 | 价格 |
|---|---|
| 1g | ￥咨询 |
产品咨询：info@biopcr.com
产品订购：sales@biopcr.com
技术支持：tech@biopcr.com
服务热线：400-860-6200
详细介绍
产品名称：Ado-Trastuzumab Emtansine生物类似药-科研级
别名：Ado-Trastuzumab Emtansine Biosimilar-Research Grade, Receptor tyrosine-protein kinase erbB-2, MLN 19, HER2, HER2/neu
宿主：Humanized
亚型：Human IgG1
浓度：1.0 - 5.0 mg/ml
反应性：Human
特异性：Detects human HER2. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Ado-trastuzumab emtansine.
存储溶液：Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
储存条件：Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
推荐同型对照（Isotype Control）：Bulk Human IgG1 Isotype Control (IB1) [ICH2254]
推荐缓冲液（Buffer）：体内抗体缓冲液pH5.0；体内抗体缓冲液pH7.4；体内抗体缓冲液pH8.0
靶点（Target）: HER2
UniProt：P04626
纯化方法（Purification method）： This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
背景资料（Background）：Ado-trastuzumab emtansine is a HER2-targeted antibody-drug conjugate which contains the humanized anti-HER2 IgG1, trastuzumab, covalently linked to the microtubule inhibitory drug DM1 via the stable thioether linker MCC. Trastuzumab is produced by Chinese hamster ovary cells, and DM1-MCC are produced by chemical synthesis. Ado-trastuzumab emtansine contains an average of 3.5 DM1 molecules per antibody.
内毒素（Endotoxin）：≤ 1.0 EU/mg as determined by the LAL method
纯度（Purity）：>95% by SDS-PAGE and HPLC
产品使用（Use）：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件：Blue ice
返回列表
推荐缓冲液（Buffer）：体内抗体缓冲液pH5.0；体内抗体缓冲液pH7.4；体内抗体缓冲液pH8.0
靶点（Target）: HER2
UniProt：P04626
纯化方法（Purification method）： This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
背景资料（Background）：Ado-trastuzumab emtansine is a HER2-targeted antibody-drug conjugate which contains the humanized anti-HER2 IgG1, trastuzumab, covalently linked to the microtubule inhibitory drug DM1 via the stable thioether linker MCC. Trastuzumab is produced by Chinese hamster ovary cells, and DM1-MCC are produced by chemical synthesis. Ado-trastuzumab emtansine contains an average of 3.5 DM1 molecules per antibody.
内毒素（Endotoxin）：≤ 1.0 EU/mg as determined by the LAL method
纯度（Purity）：>95% by SDS-PAGE and HPLC
产品使用（Use）：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件：Blue ice
