Etanercept生物类似药-研究级
货号:ICH4022-5mg
品牌:ichorbio
产品特性
英文名称: Etanercept Biosimilar - Research Grade
内毒素水平≤ 1.0 EU/mg
纯度:>95% by SDS-PAGE and HPLC
特异性:Detects human TNF. This non-therapeutic fusion-protein uses the same sequence as the therapeutic Etanercept.
规格 | 价格 |
---|---|
5mg | ¥咨询 |
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详细介绍
产品名称:Etanercept生物类似药-研究级
别名:Etanercept Biosimilar-Research Grade, Tumor necrosis factor
宿主:Humanized
浓度:1.0 - 5.0 mg/ml
反应性:Human
特异性:Detects human TNF. This non-therapeutic fusion-protein uses the same sequence as the therapeutic Etanercept.
存储溶液:Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
储存条件:Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
推荐缓冲液(Buffer):体内抗体缓冲液pH5.0;体内抗体缓冲液pH7.4;体内抗体缓冲液pH8.0
靶点(Target): TNF alpha
UniProt:P01375
纯化方法(Purification method): This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
背景资料(Background):Etanercept biosimilar is a dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1. Etanercept biosimilar is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids and has an apparent molecular weight of approximately 150 kilodaltons.
内毒素(Endotoxin):≤ 1.0 EU/mg as determined by the LAL method
纯度(Purity):>95% by SDS-PAGE and HPLC
产品使用(Use):Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件:Blue ice
返回列表
靶点(Target): TNF alpha
UniProt:P01375
纯化方法(Purification method): This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
背景资料(Background):Etanercept biosimilar is a dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1. Etanercept biosimilar is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids and has an apparent molecular weight of approximately 150 kilodaltons.
内毒素(Endotoxin):≤ 1.0 EU/mg as determined by the LAL method
纯度(Purity):>95% by SDS-PAGE and HPLC
产品使用(Use):Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件:Blue ice