Theralizumab生物类似药-研究级
货号：ICH5023-100mg
品牌：ichorbio
产品特性
英文名称: Theralizumab Biosimilar - Research Grade
内毒素水平≤ 1.0 EU/mg
纯度：>95% by SDS-PAGE
应用: Functional Assays.
| 规格 | 价格 |
|---|---|
| 100mg | ￥咨询 |
产品咨询：info@biopcr.com
产品订购：sales@biopcr.com
技术支持：tech@biopcr.com
服务热线：400-860-6200
详细介绍
产品名称：Theralizumab生物类似药-研究级
别名：Theralizumab Biosimilar-Research Grade, TGN1412, CD28-SuperMAB, TAB08
应用：Functional Assays
亚型：Human IgG4
浓度：5mg/ml
反应性：Human
特异性：Detects human CD28. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Theralizumab.
存储溶液：Sterile, preservative-free, solution in PBS. BSA and Azide free.
储存条件：This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
推荐同型对照（Isotype Control）：Bulk Human IgG4 Isotype Control (IB4) [ICH2257]
推荐缓冲液（Buffer）：体内抗体缓冲液pH7.4
靶点（Target）: CD28
UniProt：P10747
纯化方法（Purification method）： This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
背景资料（Background）：Theralizumab GN1412 is a humanised monoclonal antibody that not only binds to, but is a strong agonist for, the CD28 receptor of the immune system’s T cells. CD28 is the co-receptor for the T cell receptor; It binds to receptors on the interacting partner in the reaction through one of its ligands (B7 family). It was withdrawn from development after inducing severe inflammatory reactions as well as chronic organ failure in the first-in-human study by PAREXEL in London in March 2006.
内毒素（Endotoxin）：≤ 1.0 EU/mg as determined by the LAL method
纯度（Purity）：>95% by SDS-PAGE
应用说明（Application Notes）：This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
产品使用（Use）：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件：Blue ice
返回列表
推荐缓冲液（Buffer）：体内抗体缓冲液pH7.4
靶点（Target）: CD28
UniProt：P10747
纯化方法（Purification method）： This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
背景资料（Background）：Theralizumab GN1412 is a humanised monoclonal antibody that not only binds to, but is a strong agonist for, the CD28 receptor of the immune system’s T cells. CD28 is the co-receptor for the T cell receptor; It binds to receptors on the interacting partner in the reaction through one of its ligands (B7 family). It was withdrawn from development after inducing severe inflammatory reactions as well as chronic organ failure in the first-in-human study by PAREXEL in London in March 2006.
内毒素（Endotoxin）：≤ 1.0 EU/mg as determined by the LAL method
纯度（Purity）：>95% by SDS-PAGE
应用说明（Application Notes）：This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
产品使用（Use）：Products are for research use only. Not for use in diagnostic or therapeutic procedures.
运输条件：Blue ice
