Murine Anti-Factor IX抗体(GMA-134)
货号：GMA-134
品牌：Greenmoab
产品特性
Specificity：Human FIX (148T)
Immunogen：Human FIX peptide (Ac-SKLTRAETVFPDVDYC- amide) conjugated to KLH.
Application：ELISA and Immunoblotting
| 规格 | 价格 |
|---|---|
| 0.1 mg | ￥咨询 |
| 0.5 mg | ￥咨询 |
产品咨询：info@biopcr.com
产品订购：sales@biopcr.com
技术支持：tech@biopcr.com
服务热线：400-860-6200
详细介绍
产品名称：Murine Anti-Factor IX抗体(GMA-134)
别名：Murine Anti-Factor IX Antibody；Murine Anti-Factor IX Monoclonal Antibody；Murine Anti-Factor IX单克隆抗体；小鼠抗Factor IX抗体；小鼠抗FIX抗体；Murine Anti-Factor IX抗体；小鼠抗凝血因子IX抗体；Mouse Anti-Factor IX Antibody；F9抗体
克隆号（Clone）：GMA-134
背景介绍（Background）：
Factor IX (FIX) is a vitamin K-dependent zymogen that plays an essential role in the coagulation cascade leading to thrombus formation. In the presence of calcium, activated Factor IX (FIXa) complexes with Factor VIIIa on phospholipid surfaces to create the tenase complex, which converts Factor X to its activated form. A polymorphism is found in plasma-derived FIX within the activation peptide. The amino acid at position 148 exists as either a threonine or an alanine. GMA-134 (previously known as GMA-133) binds to FIX with threonine at the 148 position and detects FIX (148T) in ELISA and Western blot formats with no detectable binding to FIX (148A). In addition, bound GMA-134 captures FIX (148T) by bio-layer interferometry.
种属反应性（Species Reactivity）: Human
来源（Source）： Murine
特异性（Specificity）： Human FIX (148T)
免疫原（Immunogen）： Human FIX peptide (Ac-SKLTRAETVFPDVDYC- amide) conjugated to KLH.
亚型（Isotype）： IgG2a
应用（Application）：
ELISA： Binds immobilized Human FIX (148T).
Immunoblotting： Western blotting detects Human FIX (148T) under reduced conditions.
Inhibition： Does not prolong plasma clot time in APTT clotting assay.
BLI： KD= 4 nM (kdis=47x10-3 sec-1) by bio-layer interferometry
储存（Storage）：Aliquot and store at -20℃ for prolonged periods. Avoid freeze-thaw cycles. Alternatively, add 0.02% (w/v) sodium azide and store at 4℃.
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背景介绍（Background）：
Factor IX (FIX) is a vitamin K-dependent zymogen that plays an essential role in the coagulation cascade leading to thrombus formation. In the presence of calcium, activated Factor IX (FIXa) complexes with Factor VIIIa on phospholipid surfaces to create the tenase complex, which converts Factor X to its activated form. A polymorphism is found in plasma-derived FIX within the activation peptide. The amino acid at position 148 exists as either a threonine or an alanine. GMA-134 (previously known as GMA-133) binds to FIX with threonine at the 148 position and detects FIX (148T) in ELISA and Western blot formats with no detectable binding to FIX (148A). In addition, bound GMA-134 captures FIX (148T) by bio-layer interferometry.
种属反应性（Species Reactivity）: Human
来源（Source）： Murine
特异性（Specificity）： Human FIX (148T)
免疫原（Immunogen）： Human FIX peptide (Ac-SKLTRAETVFPDVDYC- amide) conjugated to KLH.
亚型（Isotype）： IgG2a
应用（Application）：
ELISA： Binds immobilized Human FIX (148T).
Immunoblotting： Western blotting detects Human FIX (148T) under reduced conditions.
Inhibition： Does not prolong plasma clot time in APTT clotting assay.
BLI： KD= 4 nM (kdis=47x10-3 sec-1) by bio-layer interferometry
储存（Storage）：Aliquot and store at -20℃ for prolonged periods. Avoid freeze-thaw cycles. Alternatively, add 0.02% (w/v) sodium azide and store at 4℃.
